LAEL147_000397000

3-hydroxy-3-methylglutaryl-CoA synthase, putative
Leishmania aethiopica L147 OG6: OG6_101064 OG7: OG7_0006553 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000573900
hypothetical protein, conserved
— OG7
LAEL147_000011500 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LAEL147_000684500 ⚠
protein kinase, putative
— OG7
LAEL147_000536900 ⚠
serine/threonine protein kinase, putative
— OG7
LAEL147_000816800 ⚠
SNF1-related protein kinases, putative
— OG7
LAEL147_000753200 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LAEL147_000498400 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LAEL147_000007800 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LAEL147_000503400 ⚠
protein kinase, putative
— OG7
LAEL147_000428600 ⚠
aminopeptidase-like protein
— OG7
LAEL147_000172000 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LAEL147_000313300 ⚠
serine/threonine-protein kinase-like protein
— OG7
LAEL147_000771800 ⚠
adenine aminohydrolase
— OG7
LAEL147_000210200 ⚠
sterol carrier protein, putative
— OG7
LAEL147_000442800
cytochrome c oxidase subunit V, putative
— Both
LAEL147_000784800
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LAEL147_000782100
glycerol kinase, glycosomal, putative
— Both
LAEL147_000299300
cytidine triphosphate synthase, putative
— Both
LAEL147_000219400 ⚠
C-terminal domain of 1-Cys peroxiredoxin, put
— Both
LAEL147_000350900 ⚠
peroxidoxin
— Both
LAEL147_000219200 ⚠
C-terminal domain of 1-Cys peroxiredoxin, put
— Both
LAEL147_000219300 ⚠
AhpC/TSA family/C-terminal domain of 1-Cys pe
— Both
LAEL147_000884600 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LAEL147_000644700 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LAEL147_000421800 ⚠
elongation factor 2-like protein
— OG7
LAEL147_000469500 ⚠
choline kinase
— OG7
LAEL147_000673200 ⚠
hypothetical protein
— OG7
LAEL147_000786800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000427200 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LAEL147_000621800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000588200 ⚠
nucleolar protein, putative
— OG7
LAEL147_000536700 ⚠
NOL1/NOP2/sun family, putative
— OG7
LAEL147_000751300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000361200 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LAEL147_000647400 ⚠
NOL1/NOP2/sun family, putative
— OG7
LAEL147_000673300 ⚠
hypothetical protein
— OG7
LAEL147_000540900 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000421300 ⚠
dullard-like phosphatase domain containing pr
— OG7
LAEL147_000500400 ⚠
NOL1/NOP2/sun family, putative
— OG7
LAEL147_000776900 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LAEL147_000773500 ⚠
protein kinase, putative
— OG7
LAEL147_000148600 ⚠
serine/threonine protein kinase, putative
— OG7
LAEL147_000006100 ⚠
serine/threonine protein kinase, putative
— OG7
LAEL147_000263400
aconitase, putative
— Both
LAEL147_000764300 ⚠
choline/ethanolamine kinase, putative
— Both
LAEL147_000422200
KIF-1 binding protein C terminal, putative
— Both
LAEL147_000491000
ribonucleoside-diphosphate reductase large ch
— Both
LAEL147_000582000
hypothetical protein, conserved
— Both
LAEL147_000433800
aspartate--ammonia ligase, putative
— Both
LAEL147_000841300
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.