LAEL147_000491000

ribonucleoside-diphosphate reductase large chain, putative
Leishmania aethiopica L147 OG6: OG6_100448 OG7: OG7_0004229 112 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 112 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000884600 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LAEL147_000067200
methylthioadenosine phosphorylase, putative
— Both
LAEL147_000784800
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LAEL147_000229400
aspartate carbamoyltransferase, putative
— Both
LAEL147_000551800
N-acetyltransferase B complex (NatB) non cata
— Both
LAEL147_000399500
n-terminal acetyltransferase complex ard1 sub
— Both
LAEL147_000133800
isocitrate dehydrogenase [NADP], mitochondria
— Both
LAEL147_000153700
anion-transporting ATPase-like protein
— Both
LAEL147_000582000
hypothetical protein, conserved
— Both
LAEL147_000640200
hypothetical protein, conserved
— Both
LAEL147_000675800
PSP1 C-terminal conserved region containing p
— Both
LAEL147_000673500 ⚠
NLI interacting factor-like phosphatase, puta
— Both
LAEL147_000586200
5-methyltetrahydropteroyltriglutamate-homocys
— Both
LAEL147_000863200 ⚠
translation initiation factor 2 subunit, puta
— Both
LAEL147_000688400
hypothetical protein, conserved
— Both
LAEL147_000861600
paraflagellar rod component, putative
— Both
LAEL147_000538900
Leucine-rich repeat, putative
— Both
LAEL147_000139900 ⚠
Adenosine/AMP deaminase, putative
— Both
LAEL147_000392900 ⚠
calcium/calmodulin-dependent protein kinase,
— Both
LAEL147_000485900 ⚠
DIS3-like exonuclease, putative
— Both
LAEL147_000484800 ⚠
rrp44p homologue, putative
— OG7
LAEL147_000049200 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LAEL147_000771800 ⚠
adenine aminohydrolase
— OG7
LAEL147_000573900
hypothetical protein, conserved
— OG7
LAEL147_000776900 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LAEL147_000421300 ⚠
dullard-like phosphatase domain containing pr
— OG7
LAEL147_000540900 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000673300 ⚠
hypothetical protein
— OG7
LAEL147_000254200 ⚠
NOL1/NOP2/sun family, putative
— OG7
LAEL147_000210200 ⚠
sterol carrier protein, putative
— OG7
LAEL147_000269100 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LAEL147_000179200 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAEL147_000369600 ⚠
aminoacyclase, putative
— OG7
LAEL147_000153000 ⚠
aminopeptidase, putative
— OG7
LAEL147_000554200 ⚠
heat shock protein grpe
— OG7
LAEL147_000500700 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAEL147_000553700 ⚠
nuclear movement protein, putative
— OG7
LAEL147_000638000 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAEL147_000152900 ⚠
aminopeptidase, putative
— OG7
LAEL147_000668200 ⚠
heat shock protein 83-17
— OG7
LAEL147_000767200 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LAEL147_000006100 ⚠
serine/threonine protein kinase, putative
— OG7
LAEL147_000751300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000621800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000427200 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LAEL147_000786800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000673200 ⚠
hypothetical protein
— OG7
LAEL147_000206000 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LAEL147_000221000 ⚠
ubiquitin hydrolase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.