LAEL147_000738500

ruvb-like 1 DNA helicase, putative
Leishmania aethiopica L147 OG6: OG6_101792 OG7: OG7_0003574 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000333000 ⚠
centromere/microtubule binding protein cbf5,
— +1 more Both
LAEL147_000728800 ⚠
ATP-dependent DNA helicase, putative
— Both
LAEL147_000731300 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LAEL147_000060700 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LAEL147_000597400 ⚠
Peptidase family M20/M25/M40, putative
— OG7
LAEL147_000597200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LAEL147_000561600 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LAEL147_000884300 ⚠
prolyl oligopeptidase, putative
— OG7
LAEL147_000369600 ⚠
aminoacyclase, putative
— OG7
LAEL147_000170700 ⚠
N-acyl-L-amino acid amidohydrolase
— OG7
LAEL147_000704000 ⚠
malate dehydrogenase, putative
— OG7
LAEL147_000282400 ⚠
glycosomal malate dehydrogenase
— OG7
LAEL147_000201100 ⚠
Sodium/hydrogen exchanger family, putative
— OG7
LAEL147_000174700 ⚠
protein kinase A regulatory subunit, putative
— OG7
LAEL147_000853000 ⚠
hs1vu complex proteolytic subunit-like, threo
— Both
LAEL147_000556700 ⚠
conserved hypothetical protein, putative
— OG7
LAEL147_000219800 ⚠
protein kinase, putative
— OG7
LAEL147_000663900 ⚠
cAMP response protein, putative
— OG7
LAEL147_000038100 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
LAEL147_000023800 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
LAEL147_000023900 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
LAEL147_000024100 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LAEL147_000023600 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
LAEL147_000024000 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
LAEL147_000537800 ⚠
conserved hypothetical protein, putative
— OG7
LAEL147_000337300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LAEL147_000268800 ⚠
protein kinase A catalytic subunit
— OG6
LAEL147_000791600 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LAEL147_000792100 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LAEL147_000842600 ⚠
fibrillarin
— Both
LAEL147_000276100 ⚠
fibrillarin, putative
— Both
LAEL147_000581900 ⚠
MORN repeat, putative
— Both
LAEL147_000571000 ⚠
SET domain containing protein, putative
— Both
LAEL147_000218900 ⚠
glutamate dehydrogenase
— Both
LAEL147_000173200 ⚠
WD40 repeats, putative
— Both
LAEL147_000164700 ⚠
cysteinyl-tRNA synthetase, putative
— Both
LAEL147_000630400 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LAEL147_000597300 ⚠
hypothetical protein
— OG7
LAEL147_000291200 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LAEL147_000528800 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LAEL147_000704100 ⚠
lactate/malate dehydrogenase, alpha/beta C-te
— OG7
LAEL147_000703800 ⚠
malate dehydrogenase, putative
— OG7
LAEL147_000703900 ⚠
malate dehydrogenase
— OG7
LAEL147_000075300 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
LAEL147_000311000 ⚠
hypothetical protein
— OG7
LAEL147_000062900 ⚠
trypanothione reductase
— OG7
LAEL147_000075700 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
LAEL147_000027000 ⚠
hypothetical protein
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.