LAEL147_000739500

Programmed cell death protein 2, C-terminal putative domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_136955 OG7: OG7_0004545 80 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 80 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000087600 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LAEL147_000665800 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000447100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000536300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000567200 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LAEL147_000583300 ⚠
DNA ligase I, putative
— OG7
LAEL147_000812300 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LAEL147_000344000 ⚠
Beta-lactamase superfamily domain containing
— OG7
LAEL147_000269000 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat, pu
— OG7
LAEL147_000526700 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000581300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000747500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000606500 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000777400 ⚠
ankyrin repeat protein, putative
— OG7
LAEL147_000051500 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LAEL147_000040500 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LAEL147_000773300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000431300 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LAEL147_000149900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000041800 ⚠
kinase-like protein
— OG7
LAEL147_000219500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000343900 ⚠
Beta-lactamase superfamily domain containing
— OG7
LAEL147_000268400 ⚠
5-oxoprolinase, putative
— OG7
LAEL147_000389700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000640200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000177500 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LAEL147_000418300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000058400 ⚠
tRNA nucleotidyltransferase, putative
— OG7
LAEL147_000463600 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000607600 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LAEL147_000781900 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LAEL147_000184600 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
LAEL147_000501200 ⚠
replication factor A, 51kDa subunit, putative
— OG7
LAEL147_000715800 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000551800 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LAEL147_000447200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000503500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000683300 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LAEL147_000700100 ⚠
tyrosyl-DNA phosphodiesterase 1
— OG7
LAEL147_000359700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LAEL147_000245000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000137100 ⚠
zinc binding dehydrogenase-like protein
— OG7
LAEL147_000262000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LAEL147_000104000 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000153700 ⚠
anion-transporting ATPase-like protein
— OG7
LAEL147_000694600 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LAEL147_000315200 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LAEL147_000180800 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LAEL147_000260500 ⚠
RNA-binding protein 29, putative
— OG7
LAEL147_000832700 ⚠
developmentally regulated GTP-binding protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.