LAEL147_000184600

Thiamin pyrophosphokinase, vitamin B1 binding domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_151510 OG7: OG7_0006221 45 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 45 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000536300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000072000 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000043700 ⚠
Ubiquitin-like domain containing protein, put
— Both
LAEL147_000031500 ⚠
casein kinase II, alpha chain, putative
— OG6
LAEL147_000043500 ⚠
TatD related DNase, putative
— Both
LAEL147_000137200 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LAEL147_000104000 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000104100 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000162400 ⚠
ribonuclease mar1
— OG7
LAEL147_000812300 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LAEL147_000262000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LAEL147_000150000 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LAEL147_000041800 ⚠
kinase-like protein
— Both
LAEL147_000447100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000245000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000653100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000801500 ⚠
tubulin tyrosine ligase, putative
— OG7
LAEL147_000570600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000739500 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LAEL147_000517200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAEL147_000715800 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000480700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000228400 ⚠
tubulin tyrosine ligase, putative
— OG7
LAEL147_000501200 ⚠
replication factor A, 51kDa subunit, putative
— Both
LAEL147_000583300 ⚠
DNA ligase I, putative
— Both
LAEL147_000567200 ⚠
C2H2 type zinc-finger (2 copies), putative
— Both
LAEL147_000359700 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LAEL147_000606500 ⚠
dihydrouridine synthase (Dus), putative
— Both
LAEL147_000700100 ⚠
tyrosyl-DNA phosphodiesterase 1
— Both
LAEL147_000323300 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LAEL147_000683300 ⚠
peptidase m20/m25/m40 family-like protein
— Both
LAEL147_000503500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000447200 ⚠
hypothetical protein, conserved
— Both
LAEL147_000551800 ⚠
N-acetyltransferase B complex (NatB) non cata
— Both
LAEL147_000344000 ⚠
Beta-lactamase superfamily domain containing
— Both
LAEL147_000343900 ⚠
Beta-lactamase superfamily domain containing
— Both
LAEL147_000781900 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LAEL147_000607600 ⚠
peptidase m20/m25/m40 family-like protein
— Both
LAEL147_000463600 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000301600 ⚠
tubulin-tyrosine ligase, putative
— Both
LAEL147_000219500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000137100 ⚠
zinc binding dehydrogenase-like protein
— Both
LAEL147_000104200 ⚠
mitochondrial associated ribonuclease, putati
— Both
LAEL147_000087600 ⚠
metallo-peptidase, Clan ME, Family M16C
— Both
LAEL147_000008500 ⚠
3-mercaptopyruvate sulfurtransferase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.