LAEL147_000348200

ATP-dependent DEAD/H RNA helicase, putative
Leishmania aethiopica L147 OG6: OG6_126543 OG7: OG7_0000698 87 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 87 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000876100
hypothetical protein, conserved
— OG6
LAEL147_000785000
Putative death-receptor fusion protein (DUF24
— OG6
LAEL147_000705600
WD domain, G-beta repeat, putative
— OG6
LAEL147_000436900
Axonemal dynein light chain, putative
— OG6
LAEL147_000870500
hypothetical protein, conserved
— OG6
LAEL147_000720400
hypothetical protein, conserved
— OG6
LAEL147_000628000
OSM3-like kinesin, putative
— OG6
LAEL147_000572300
hypothetical protein, conserved
— OG6
LAEL147_000551500
hypothetical protein, conserved
— OG6
LAEL147_000624000
hypothetical protein, conserved
— OG6
LAEL147_000395400
hypothetical protein, conserved
— OG6
LAEL147_000878400
ubiquitin-protein ligase, putative
— OG6
LAEL147_000546700
MATH domain containing protein, putative
— OG6
LAEL147_000419400
Not1 N-terminal domain, CCR4-Not complex comp
— OG6
LAEL147_000784200 ⚠
60S ribosomal subunit protein L31, putative
— OG6
LAEL147_000414800
Clusterin-associated protein-1, putative
— OG6
LAEL147_000835500
hypothetical protein, conserved
— OG6
LAEL147_000575400
Stabilization of polarity axis, putative
— OG6
LAEL147_000693900
Unc104-like kinesin, putative
— OG6
LAEL147_000583200
protein mkt1, putative
— OG6
LAEL147_000525400
kinesin, putative
— OG6
LAEL147_000682000
Tetratricopeptide repeats, putative
— OG6
LAEL147_000363700
hypothetical protein, conserved
— OG6
LAEL147_000073400
hypothetical protein, conserved
— OG6
LAEL147_000272800
Protein of unknown function (DUF3648), putati
— OG6
LAEL147_000161800
translation initiation factor EIF-2b alpha su
— OG6
LAEL147_000023400
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
LAEL147_000217900
protein phosphatase 2A regulatory subunit, pu
— OG6
LAEL147_000231200
ubiquitin hydrolase, putative
— OG6
LAEL147_000339700
proteasome regulatory ATPase subunit 1, putat
— OG6
LAEL147_000049400
hypothetical protein, conserved
— OG6
LAEL147_000543700
serine/threonine-protein kinase Nek3, putativ
— OG6
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG6
LAEL147_000767100
casein kinase II, putative
— OG6
LAEL147_000511100
Uncharacterized ACR, COG1678, putative
— OG6
LAEL147_000817700
hypothetical protein, conserved
— OG6
LAEL147_000784300 ⚠
60S ribosomal subunit protein L31, putative
— OG6
LAEL147_000698400
hypothetical protein, conserved
— OG6
LAEL147_000477300
WD domain, G-beta repeat, putative
— OG6
LAEL147_000528000
COPII coat assembly protein sec16, putative
— OG6
LAEL147_000871700
Rab3 GTPase-activating protein regulatory sub
— OG6
LAEL147_000667400
WD domain, G-beta repeat, putative
— OG6
LAEL147_000483800
hypothetical protein, conserved
— OG6
LAEL147_000445600
microtubule-associated protein, putative
— OG6
LAEL147_000552400
AMP-binding enzyme, putative
— OG6
LAEL147_000090000
ubiquitin-protein ligase-like, putative
— OG6
LAEL147_000074300 ⚠
5'-3' exonuclease, putative
— OG6
LAEL147_000826800 ⚠
exoribonuclease 2, putative
— OG6
LAEL147_000284000
CAP-Gly domain containing protein, putative
— OG6
LAEL147_000284700
WD domain, G-beta repeat, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.