LAMA_000533800

Calpain family cysteine protease/Calpain large subunit, domain III, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_115879 OG7: OG7_0021639 72 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 72 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000627000 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000699300 ⚠
hypothetical protein, conserved
— Both
LAMA_000051200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000243100 ⚠
Ribosomal protein L17, putative
— Both
LAMA_000039000 ⚠
hypothetical protein, conserved
— Both
LAMA_000183400 ⚠
hypothetical protein, conserved
— Both
LAMA_000052700 ⚠
Mitochondrial 39-S ribosomal protein L47 (MRP
— Both
LAMA_000134600 ⚠
hypothetical protein, conserved
— Both
LAMA_000533600 ⚠
Calpain family cysteine protease/Calpain larg
— +2 more Both
LAMA_000266200 ⚠
hypothetical protein, conserved
— Both
LAMA_000131200 ⚠
Ribosomal protein L9, N-terminal domain conta
— Both
LAMA_000415200 ⚠
Pentatricopeptide repeat domain/PPR repeat fa
— Both
LAMA_000128500 ⚠
Ribosomal protein L3, putative
— Both
LAMA_000230300 ⚠
hypothetical protein
— OG6
LAMA_000325900 ⚠
Ribosomal L37ae protein family, putative
— Both
LAMA_000804900 ⚠
Ribosomal protein S17, putative
— Both
LAMA_000148400 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— Both
LAMA_000721800 ⚠
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000505100 ⚠
Signal recognition particle receptor beta sub
— Both
LAMA_000226700 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000064000 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000515300 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000720700 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000277500 ⚠
Ubiquitin-like domain/CAP-Gly domain containi
— OG7
LAMA_000014900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000017300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000357500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000335300 ⚠
hypothetical protein, conserved
— Both
LAMA_000777400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000227000 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000529900 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LAMA_000226900 ⚠
hypothetical protein
— OG7
LAMA_000777600 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000294000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000079700 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000681500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000127600 ⚠
hypothetical protein
— Both
LAMA_000720000 ⚠
Coenzyme A transferase, putative
— +2 more Both
LAMA_000621200 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— Both
LAMA_000604200 ⚠
Coenzyme A transferase, putative
— +2 more Both
LAMA_000604400 ⚠
Coenzyme A transferase, putative
— +2 more Both
LAMA_000470800 ⚠
SpoU rRNA Methylase family, putative
— Both
LAMA_000596500 ⚠
DnaJ domain containing protein, putative
— Both
LAMA_000679300 ⚠
hypothetical protein, conserved
— Both
LAMA_000024100 ⚠
Ribosomal protein L13e, putative
— Both
LAMA_000604300 ⚠
Coenzyme A transferase, putative
— +2 more Both
LAMA_000025000 ⚠
Ribosomal protein S13/S18, putative
— Both
LAMA_000103800 ⚠
Ribosomal protein L13e, putative
— Both
LAMA_000715900 ⚠
Ribosomal protein L37e, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.