LAMA_000227000

Zinc finger C-x8-C-x5-C-x3-H type (and similar), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_199750 OG7: OG7_0002161 85 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 85 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000367600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000546300 ⚠
Protein tyrosine kinase/Fungal protein kinase
— OG7
LAMA_000493900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000777200 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000596500 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000107400 ⚠
Domain of unknown function (DUF4139), putativ
— OG7
LAMA_000348800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000367500 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000543800 ⚠
Snf7, putative
— OG7
LAMA_000127600 ⚠
hypothetical protein
— OG7
LAMA_000337900 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000061800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000127200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000589800 ⚠
hypothetical protein
— OG7
LAMA_000341200 ⚠
Snf7, putative
— OG7
LAMA_000343500 ⚠
NUDIX domain containing protein, putative
— OG7
LAMA_000134600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000079700 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000681500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000148400 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000183400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000241500 ⚠
Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27
— OG7
LAMA_000251400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000505100 ⚠
Signal recognition particle receptor beta sub
— OG7
LAMA_000526200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000404100 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000819400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000167600 ⚠
Ataxin 2 SM domain/LsmAD domain containing pr
— OG7
LAMA_000619900 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000417900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000171000 ⚠
GRIP domain containing protein, putative
— OG7
LAMA_000051200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000449000 ⚠
Pentatricopeptide repeat domain/PPR repeat, p
— OG7
LAMA_000009000 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000663300 ⚠
Alpha/beta hydrolase family/Serine aminopepti
— OG7
LAMA_000636500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000683100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000596900 ⚠
Flavinator of succinate dehydrogenase, putati
— OG7
LAMA_000753600 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000620400 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000777300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000503900 ⚠
Phosphoribosyl transferase domain containing
— OG7
LAMA_000081200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000554300 ⚠
Prp19/Pso4-like/WD domain, G-beta repeat, put
— OG7
LAMA_000458500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000157800 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000091100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000797600 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.