LAMA_000367500

Rab-GTPase-TBC domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101755 OG7: OG7_0001257 143 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 143 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000592800 ⚠
CS domain containing protein, putative
— OG7
LAMA_000503900 ⚠
Phosphoribosyl transferase domain containing
— Both
LAMA_000620000 ⚠
DNA ligase N terminus/ATP dependent DNA ligas
— Both
LAMA_000618600 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— Both
LAMA_000081200 ⚠
hypothetical protein, conserved
— Both
LAMA_000273700 ⚠
PPR repeat/Pentatricopeptide repeat domain/PP
— Both
LAMA_000430000 ⚠
Elongation factor Tu GTP binding domain/50S r
— Both
LAMA_000306300 ⚠
Tetratricopeptide repeat, putative
— OG6
LAMA_000553400 ⚠
Tetratricopeptide repeat/Potential Monad-bind
— OG6
LAMA_000107300 ⚠
Thioredoxin-like domain/UDP-glucose:Glycoprot
— Both
LAMA_000432800 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— Both
LAMA_000559100 ⚠
RNB domain containing protein, putative
— Both
LAMA_000776700 ⚠
PSP1 C-terminal conserved region containing p
— Both
LAMA_000171800 ⚠
PSP1 C-terminal conserved region containing p
— Both
LAMA_000378300 ⚠
PSP1 C-terminal conserved region containing p
— Both
LAMA_000636500 ⚠
hypothetical protein, conserved
— Both
LAMA_000694600 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LAMA_000070300 ⚠
hypothetical protein, conserved
— Both
LAMA_000777400 ⚠
hypothetical protein, conserved
— Both
LAMA_000447100 ⚠
HIT domain containing protein, putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000368500 ⚠
hypothetical protein, conserved
— Both
LAMA_000519400 ⚠
hypothetical protein, conserved
— Both
LAMA_000458500 ⚠
hypothetical protein, conserved
— Both
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000367000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000355200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000816500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000116600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000669600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000199500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000157600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000682800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000543800 ⚠
Snf7, putative
— OG7
LAMA_000493900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000777600 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000226900 ⚠
hypothetical protein
— OG7
LAMA_000529900 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LAMA_000227000 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000621200 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000226700 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000777200 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000369900 ⚠
Homocysteine S-methyltransferase, putative
— OG7
LAMA_000796100 ⚠
PPR repeat, putative
— OG7
LAMA_000796700 ⚠
Glyoxalase/Bleomycin resistance protein/Dioxy
— OG7
LAMA_000753600 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000467600 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.