LAMA_000618600

Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin family/UBA/TS-N domain/XPC-binding domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101279 OG7: OG7_0005081 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000465900
hypothetical protein, conserved
— Both
LAMA_000574200
X-Pro dipeptidyl-peptidase (S15 family)/Serin
— Both
LAMA_000592400
Histidyl-tRNA synthetase/Anticodon binding do
— Both
LAMA_000225700
SLOG cluster4 family/Possible lysine decarbox
— Both
LAMA_000592200
Cytochrome b5-like Heme/Steroid binding domai
— OG6
LAMA_000016600
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— Both
LAMA_000652100
Component of IIS longevity pathway SMK-1, put
— Both
LAMA_000418900
BAG domain containing protein, putative
— Both
LAMA_000505600 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG6
LAMA_000611000 ⚠
Formate--tetrahydrofolate ligase, putative
— Both
LAMA_000597400
Armadillo/beta-catenin-like repeat/Atypical A
— Both
LAMA_000616800
tRNA synthetases class I (I, L, M and V)/tRNA
— Both
LAMA_000608600
SET domain containing protein, putative
— Both
LAMA_000203600
tRNA synthetases class I (I, L, M and V)/tRNA
— Both
LAMA_000511500
Glucosidase II beta subunit-like protein, put
— Both
LAMA_000175800
hypothetical protein, conserved
— Both
LAMA_000647700
Calreticulin family, putative
— Both
LAMA_000420500
hypothetical protein, conserved
— Both
LAMA_000083600
SIS domain containing protein, putative
— Both
LAMA_000732600 ⚠
Deoxyhypusine synthase, putative
— Both
LAMA_000128200 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000107300
Thioredoxin-like domain/UDP-glucose:Glycoprot
— Both
LAMA_000793800
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— Both
LAMA_000328500 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000103100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000020000 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— Both
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— Both
LAMA_000380800 ⚠
Deoxyhypusine synthase, putative
— Both
LAMA_000285400
Aminoacyl-tRNA editing domain/tRNA synthetase
— Both
LAMA_000306300 ⚠
Tetratricopeptide repeat, putative
— OG6
LAMA_000306900
PUB domain containing protein, putative
— Both
LAMA_000404000
tRNA synthetases class I (I, L, M and V)/tRNA
— Both
LAMA_000297600 ⚠
ABC transporter, putative
— Both
LAMA_000338600 ⚠
14-3-3 protein, putative
— Both
LAMA_000113600
hypothetical protein, conserved
— Both
LAMA_000173900 ⚠
14-3-3 protein, putative
— Both
LAMA_000393700
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— Both
LAMA_000282000
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000499400
Translation initiation factor eIF3 subunit, p
— Both
LAMA_000532400 ⚠
Nucleoporin autopeptidase/Nuclear protein 96,
— Both
LAMA_000777700
Protein tyrosine kinase/Protein kinase domain
— OG6
LAMA_000620000 ⚠
DNA ligase N terminus/ATP dependent DNA ligas
— Both
LAMA_000771500
hypothetical protein, conserved
— Both
LAMA_000553400 ⚠
Tetratricopeptide repeat/Potential Monad-bind
— OG6
LAMA_000362600
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000389500
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000812000
SET domain containing protein, putative
— Both
LAMA_000388900
PRP38 family, putative
— Both
LAMA_000016200
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— Both
LAMA_000050200
S1 RNA binding domain/Eukaryotic translation
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.