LAMA_000225700

SLOG cluster4 family/Possible lysine decarboxylase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_107817 OG7: OG7_0004888 110 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 110 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000771900
hypothetical protein, conserved
— Both
LAMA_000603100 ⚠
Queuine tRNA-ribosyltransferase, putative
— Both
LAMA_000592400
Histidyl-tRNA synthetase/Anticodon binding do
— Both
LAMA_000611000 ⚠
Formate--tetrahydrofolate ligase, putative
— Both
LAMA_000592200
Cytochrome b5-like Heme/Steroid binding domai
— OG6
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— Both
LAMA_000112500
XPC-binding domain/UBA/TS-N domain containing
— Both
LAMA_000532300 ⚠
hypothetical protein
— Both
LAMA_000268400
Mak10 subunit, NatC N(alpha)-terminal acetylt
— Both
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAMA_000608600
SET domain containing protein, putative
— Both
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000016600
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— Both
LAMA_000418900
BAG domain containing protein, putative
— Both
LAMA_000511500
Glucosidase II beta subunit-like protein, put
— Both
LAMA_000175800
hypothetical protein, conserved
— Both
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000420500
hypothetical protein, conserved
— Both
LAMA_000083600
SIS domain containing protein, putative
— Both
LAMA_000273700 ⚠
PPR repeat/Pentatricopeptide repeat domain/PP
— Both
LAMA_000430000 ⚠
Elongation factor Tu GTP binding domain/50S r
— Both
LAMA_000432800
tRNA synthetases class II (A)/Threonyl and Al
— Both
LAMA_000694600
Gar1/Naf1 RNA binding region containing prote
— Both
LAMA_000070300
hypothetical protein, conserved
— Both
LAMA_000239600
Proliferating cell nuclear antigen, N-termina
— Both
LAMA_000367600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000467600 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
LAMA_000310500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000348100 ⚠
Glycosyl hydrolases family 31, putative
— OG7
LAMA_000284400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000395000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000593300 ⚠
GrpE, putative
— OG7
LAMA_000740500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000641300 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000589800 ⚠
hypothetical protein
— OG7
LAMA_000528900 ⚠
Queuine tRNA-ribosyltransferase, putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000796100 ⚠
PPR repeat, putative
— OG7
LAMA_000592800 ⚠
CS domain containing protein, putative
— OG7
LAMA_000270000 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.