LAMA_000239600

Proliferating cell nuclear antigen, N-terminal domain/Rad9/Proliferating cell nuclear antigen, C-terminal domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100882 OG7: OG7_0005136 17 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 17 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000572900
OB-fold nucleic acid binding domain/Replicati
— Both
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000771900
hypothetical protein, conserved
— Both
LAMA_000225700
SLOG cluster4 family/Possible lysine decarbox
— Both
LAMA_000620700
S-adenosylmethionine synthetase, N-terminal d
— Both
LAMA_000549400
Ribonucleotide reductase, small chain, putati
— Both
LAMA_000219700
Sodium/hydrogen exchanger family, putative
— Both
LAMA_000171700
NIF3 (NGG1p interacting factor 3), putative
— Both
LAMA_000490500
C-5 cytosine-specific DNA methylase, putative
— Both
LAMA_000653200
Insulinase (Peptidase family M16)/Peptidase M
— Both
LAMA_000528900 ⚠
Queuine tRNA-ribosyltransferase, putative
— Both
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— Both
LAMA_000021200 ⚠
Hsp70 protein, putative
— OG6
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— Both
LAMA_000603100 ⚠
Queuine tRNA-ribosyltransferase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.