LAMA_000583300

Hsp70 protein/MreB/Mbl protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100083 OG7: OG7_0000777 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— +1 more OG6
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— +1 more OG6
LAMA_000021200 ⚠
Hsp70 protein, putative
— +1 more OG6
LAMA_000452400 ⚠
hypothetical protein, conserved
— OG6
LAMA_000617700 ⚠
hypothetical protein, conserved
— Both
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— OG6
LAMA_000278400 ⚠
hypothetical protein, conserved
— Both
LAMA_000598500 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— Both
LAMA_000776200 ⚠
hypothetical protein, conserved
— Both
LAMA_000584200 ⚠
Glu/Leu/Phe/Val dehydrogenase, dimerisation d
— OG6
LAMA_000202000 ⚠
N2,N2-dimethylguanosine tRNA methyltransferas
— Both
LAMA_000125500 ⚠
STI1 domain containing protein, putative
— Both
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— Both
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— Both
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— Both
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG6
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000415500 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000411500 ⚠
V-ATPase subunit H, putative
— Both
LAMA_000337300 ⚠
ATP synthase (E/31 kDa) subunit, putative
— Both
LAMA_000014200 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG6
LAMA_000148500 ⚠
Uncharacterised protein family (UPF0160), put
— OG6
LAMA_000030200 ⚠
AMP-binding enzyme, putative
— OG6
LAMA_000032500 ⚠
AMP-binding enzyme, putative
— OG6
LAMA_000042700 ⚠
AMP-binding enzyme, putative
— OG6
LAMA_000423100 ⚠
tRNA-methyltransferase O, putative
— Both
LAMA_000440100 ⚠
AMP-binding enzyme/AMP-binding enzyme C-termi
— OG6
LAMA_000336500 ⚠
3' exoribonuclease family, domain 1/3' exorib
— OG6
LAMA_000433200 ⚠
3' exoribonuclease family, domain 1, putative
— OG6
LAMA_000690100 ⚠
3' exoribonuclease family, domain 1/3' exorib
— OG6
LAMA_000672700 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG6
LAMA_000021900 ⚠
EF-1 guanine nucleotide exchange domain conta
— OG6
LAMA_000737100 ⚠
EF-1 guanine nucleotide exchange domain conta
— OG6
LAMA_000320600 ⚠
EF-1 guanine nucleotide exchange domain conta
— OG6
LAMA_000423700 ⚠
hypothetical protein, conserved
— Both
LAMA_000444800 ⚠
SET domain containing protein, putative
— OG7
LAMA_000636000
SPRY domain containing protein, putative
— OG7
LAMA_000310700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000158000
hypothetical protein, conserved
— OG7
LAMA_000220700 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000227200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000125800 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000530200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000193200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000084200 ⚠
SET domain/MYND finger containing protein, pu
— OG7
LAMA_000444600 ⚠
SET domain containing protein, putative
— OG7
LAMA_000136500 ⚠
SET domain containing protein, putative
— OG7
LAMA_000739200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000471700 ⚠
SET domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.