LAMA_000054400

Domain of unknown function (DUF1935)/Calpain family cysteine protease, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_127587 OG7: OG7_0001161 119 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 119 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG6
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG6
LAMA_000796000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG6
LAMA_000715300 ⚠
Histone-binding protein RBBP4 or subunit C of
— OG6
LAMA_000274400 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG6
LAMA_000285900 ⚠
hypothetical protein, conserved
— OG6
LAMA_000196000 ⚠
Radial spokehead-like protein, putative
— OG6
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LAMA_000593700 ⚠
hypothetical protein, conserved
— OG6
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000021200 ⚠
Hsp70 protein, putative
— OG6
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000073300 ⚠
MORN repeat, putative
— OG6
LAMA_000423100 ⚠
tRNA-methyltransferase O, putative
— OG6
LAMA_000315700 ⚠
hypothetical protein, conserved
— OG6
LAMA_000582600 ⚠
Uncharacterized ACR, COG1678, putative
— OG6
LAMA_000548100 ⚠
Protein tyrosine kinase/Kinase-like/Protein k
— OG6
LAMA_000563400 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG6
LAMA_000451500 ⚠
Inositol hexakisphosphate, putative
— OG6
LAMA_000364000 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG6
LAMA_000466400 ⚠
hypothetical protein, conserved
— OG6
LAMA_000362800 ⚠
hypothetical protein, conserved
— OG6
LAMA_000456600 ⚠
hypothetical protein, conserved
— OG6
LAMA_000612500 ⚠
Stabilization of polarity axis, putative
— OG6
LAMA_000800300 ⚠
Putative death-receptor fusion protein (DUF24
— OG6
LAMA_000768100 ⚠
Pyruvate kinase, barrel domain/Pyruvate kinas
— OG6
LAMA_000031500 ⚠
Aspartyl protease/gag-polyprotein putative as
— OG6
LAMA_000473300 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG6
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— OG6
LAMA_000520200 ⚠
hypothetical protein, conserved
— OG6
LAMA_000766500 ⚠
Gar1/Naf1 RNA binding region containing prote
— OG6
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— OG6
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG6
LAMA_000202000 ⚠
N2,N2-dimethylguanosine tRNA methyltransferas
— OG6
LAMA_000236100 ⚠
Bacterial NAD-glutamate dehydrogenase/Glutama
— OG6
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— OG6
LAMA_000774200 ⚠
ATP synthase subunit D, putative
— OG6
LAMA_000501300 ⚠
hypothetical protein, conserved
— OG6
LAMA_000147500 ⚠
Putative zinc finger in N-recognin (UBR box),
— OG6
LAMA_000141900 ⚠
AAA domain (dynein-related subfamily)/AAA dom
— OG6
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG6
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG6
LAMA_000493000 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG6
LAMA_000168600 ⚠
hypothetical protein, conserved
— OG6
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG6
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG6
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG6
Page 1 of 3
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.