LAMA_000593700

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_113914 OG7: OG7_0021257 117 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 117 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— Both
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— +2 more Both
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— +2 more Both
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— +2 more Both
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— +2 more Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000068300
Surp module, putative
— Both
LAMA_000279700
hypothetical protein, conserved
— Both
LAMA_000181300
hypothetical protein, conserved
— Both
LAMA_000473300
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LAMA_000425900
hypothetical protein, conserved
— Both
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— Both
LAMA_000524500
WD domain, G-beta repeat, putative
— Both
LAMA_000291700
CrtC N-terminal lipocalin domain/Lipocalin-li
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000591800
hypothetical protein, conserved
— Both
LAMA_000474600
Tubulin folding cofactor D C terminal, putati
— Both
LAMA_000384900
hypothetical protein, conserved
— Both
LAMA_000186600
Pyridoxal-dependent decarboxylase, pyridoxal
— Both
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000732400 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000453900 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000435500 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000317300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000542900
hypothetical protein, conserved
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000371900
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000513200 ⚠
RNA pseudouridylate synthase, putative
— OG7
LAMA_000052500 ⚠
RNA pseudouridylate synthase, putative
— OG7
LAMA_000418000 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG7
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000808900 ⚠
SacI homology domain containing protein, puta
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000462000 ⚠
SacI homology domain/Protein of unknown funct
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.