LAMA_000279700

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_141922 OG7: OG7_0006056 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000415800 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000418000 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000194900 ⚠
Kinesin motor domain/Microtubule binding/TRAF
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000075500 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000187600 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000411000 ⚠
Ring finger domain/RING-H2 zinc finger domain
— OG7
LAMA_000143200 ⚠
Ring finger domain/RING-H2 zinc finger domain
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000676000 ⚠
Importin repeat, putative
— OG7
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000186600
Pyridoxal-dependent decarboxylase, pyridoxal
— Both
LAMA_000181300
hypothetical protein, conserved
— Both
LAMA_000678700
hypothetical protein, conserved
— Both
LAMA_000435500 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000371900
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000513200 ⚠
RNA pseudouridylate synthase, putative
— OG7
LAMA_000052500 ⚠
RNA pseudouridylate synthase, putative
— OG7
LAMA_000626000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000258900 ⚠
Anaphase-promoting complex subunit 11 RING-H2
— OG7
LAMA_000335500 ⚠
Ring finger domain/RING-like zinc finger/RING
— OG7
LAMA_000026100 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000453900 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000306000 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000481600 ⚠
Ring finger domain containing protein, putati
— OG7
LAMA_000541100 ⚠
RING-H2 zinc finger domain/Ring finger domain
— OG7
LAMA_000791100 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000732400 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000763200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000351000 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000297100
hypothetical protein, conserved
— Both
LAMA_000637100
hypothetical protein, conserved
— Both
LAMA_000726400
hypothetical protein, conserved
— Both
LAMA_000593700
hypothetical protein, conserved
— Both
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— Both
LAMA_000460000 ⚠
Microtubule binding/Kinesin motor domain cont
— Both
LAMA_000619200
EF hand/EF-hand domain pair, putative
— Both
LAMA_000566100
hypothetical protein, conserved
— Both
LAMA_000789300
Helicase conserved C-terminal domain containi
— OG6
LAMA_000452000 ⚠
RING-H2 zinc finger domain/Zinc finger, C3HC4
— Both
LAMA_000384900
hypothetical protein, conserved
— Both
LAMA_000386700
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.