LAMA_000763200

HECT-domain (ubiquitin-transferase), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_158358 OG7: OG7_0002947 152 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 152 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000699000 ⚠
MutS domain III/MutS family domain IV/MutS do
— OG7
LAMA_000502800 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000665000 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000598300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000027400 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000072200 ⚠
Rhodanese-like domain/Domain of unknown funct
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000442100 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000575000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000572900 ⚠
OB-fold nucleic acid binding domain/Replicati
— OG7
LAMA_000299500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000245400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000538300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000236100 ⚠
Bacterial NAD-glutamate dehydrogenase/Glutama
— OG7
LAMA_000767200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000751300 ⚠
Methyltransferase involved in Williams-Beuren
— OG7
LAMA_000405800 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
LAMA_000423700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000068300 ⚠
Surp module, putative
— OG7
LAMA_000279700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000088300 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— OG7
LAMA_000179200 ⚠
PUB domain containing protein, putative
— OG7
LAMA_000794200 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAMA_000751400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000799400 ⚠
Pex19 protein family, putative
— OG7
LAMA_000726400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000715300 ⚠
Histone-binding protein RBBP4 or subunit C of
— OG7
LAMA_000356600 ⚠
Calponin homology (CH) domain containing prot
— OG7
LAMA_000814500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000083500 ⚠
TLD, putative
— OG7
LAMA_000150500 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
LAMA_000288600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAMA_000167900 ⚠
Zinc finger, C3HC4 type (RING finger)/Prokary
— OG7
LAMA_000153000 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAMA_000514400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000619200 ⚠
EF hand/EF-hand domain pair, putative
— OG7
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000326300 ⚠
TLD, putative
— OG7
LAMA_000044600 ⚠
TLD, putative
— OG7
LAMA_000385100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000386700 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.