LAMA_000405800

Domain of unknown function (DUF4042), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_158058 OG7: OG7_0008375 110 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 110 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000751400
hypothetical protein, conserved
— Both
LAMA_000513400
hypothetical protein, conserved
— Both
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000285400
Aminoacyl-tRNA editing domain/tRNA synthetase
— Both
LAMA_000600500 ⚠
tRNA pseudouridine synthase, putative
— Both
LAMA_000179200
PUB domain containing protein, putative
— Both
LAMA_000299500
hypothetical protein, conserved
— Both
LAMA_000132900
WD domain, G-beta repeat, putative
— Both
LAMA_000178900
Leucine Rich repeat, putative
— Both
LAMA_000012800
Soluble NSF attachment protein, SNAP, putativ
— Both
LAMA_000283700
Hydantoinase/oxoprolinase N-terminal region/H
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000732400 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000507600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000478000 ⚠
Glycosyl transferase family 2, putative
— OG7
LAMA_000811100 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000626200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000495300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000791100 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000083500 ⚠
TLD, putative
— OG7
LAMA_000326300 ⚠
TLD, putative
— OG7
LAMA_000336300 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000027400 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000598300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000388300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000626600 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAMA_000593200 ⚠
GrpE, putative
— OG7
LAMA_000763900 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000351000 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000763200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.