LAMA_000012800

Soluble NSF attachment protein, SNAP, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146739 OG7: OG7_0042723 85 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 85 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000235700
ThiF family, putative
— Both
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000336300 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000626200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000039800
Nop14-like family, putative
— Both
LAMA_000405800
Domain of unknown function (DUF4042), putativ
— Both
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000602700
CLASP N terminal, putative
— Both
LAMA_000304500 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— Both
LAMA_000104800
Aminopeptidase I zinc metalloprotease (M18)/M
— Both
LAMA_000409300
hypothetical protein, conserved
— Both
LAMA_000181600 ⚠
Elongation factor Tu GTP binding domain/Elong
— Both
LAMA_000132900
WD domain, G-beta repeat, putative
— Both
LAMA_000180200
Pyruvate phosphate dikinase, PEP/pyruvate bin
— Both
LAMA_000266300 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— OG6
LAMA_000115400 ⚠
Hsp70 protein/Tetratricopeptide repeat, putat
— Both
LAMA_000042100
hypothetical protein, conserved
— Both
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000626300 ⚠
hypothetical protein
— OG7
LAMA_000283700
Hydantoinase/oxoprolinase N-terminal region/H
— Both
LAMA_000763900 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000626600 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000548400
LSM domain containing protein, putative
— Both
LAMA_000516300 ⚠
Prenyltransferase and squalene oxidase repeat
— Both
LAMA_000232500
hypothetical protein, conserved
— Both
LAMA_000106300
Leucine-rich repeat/Leucine rich repeat, puta
— Both
LAMA_000489300
hypothetical protein, conserved
— OG6
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— Both
LAMA_000285400
Aminoacyl-tRNA editing domain/tRNA synthetase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.