LAMA_000180200

Pyruvate phosphate dikinase, PEP/pyruvate binding domain/PEP-utilising enzyme, mobile domain/PEP-utilising enzyme, TIM barrel domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100727 OG7: OG7_0004964 118 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 118 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000559100 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000225400 ⚠
TATA box binding protein associated factor (T
— Both
LAMA_000780200 ⚠
TATA box binding protein associated factor (T
— Both
LAMA_000579400
ATP synthase alpha/beta family, beta-barrel d
— Both
LAMA_000031500
Aspartyl protease/gag-polyprotein putative as
— Both
LAMA_000346000
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— Both
LAMA_000760000
ATP synthase alpha/beta family, beta-barrel d
— Both
LAMA_000503100
Glycine cleavage system P-protein, putative
— Both
LAMA_000236100
Bacterial NAD-glutamate dehydrogenase/Glutama
— Both
LAMA_000434700
AhpC/TSA family/Redoxin/C-terminal domain of
— Both
LAMA_000437900
Vacuolar (H+)-ATPase G subunit, putative
— Both
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— Both
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— Both
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— Both
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000078900
Glutamine synthetase, beta-Grasp domain/Gluta
— Both
LAMA_000337300
ATP synthase (E/31 kDa) subunit, putative
— Both
LAMA_000042100
hypothetical protein, conserved
— Both
LAMA_000729900
Glucose-6-phosphate dehydrogenase, NAD bindin
— Both
LAMA_000042400
Aldehyde dehydrogenase family, putative
— Both
LAMA_000012800
Soluble NSF attachment protein, SNAP, putativ
— Both
LAMA_000061900
hypothetical protein, conserved
— Both
LAMA_000749800 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000264200 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000264000 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000473100 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000515300 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000720700 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000107800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000421900 ⚠
Acetyltransferase (GNAT) family/Acetyltransfe
— OG7
LAMA_000069200 ⚠
Cyclin, putative
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000291300 ⚠
Metallopeptidase family M24, putative
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000487100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000311400 ⚠
Ubiquitin family/UBA/TS-N domain containing p
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000052500 ⚠
RNA pseudouridylate synthase, putative
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.