LAMA_000078900

Glutamine synthetase, beta-Grasp domain/Glutamine synthetase, catalytic domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100668 OG7: OG7_0003785 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000435400
MobA-like NTP transferase domain/Nucleotidyl
— Both
LAMA_000422300
hypothetical protein, conserved
— Both
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— Both
LAMA_000644600
hypothetical protein, conserved
— Both
LAMA_000347500
hypothetical protein, conserved
— Both
LAMA_000299100
WD domain, G-beta repeat, putative
— Both
LAMA_000136600 ⚠
Helix-hairpin-helix domain/Fingers domain of
— Both
LAMA_000552500 ⚠
50S ribosome-binding GTPase/Protein of unknow
— Both
LAMA_000396700
hypothetical protein, conserved
— Both
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— Both
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— Both
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— Both
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000604400 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000604200 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000720000 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000604300 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000346000
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— Both
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000686600 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LAMA_000547000 ⚠
50S ribosome-binding GTPase/Ferrous iron tran
— OG7
LAMA_000136700 ⚠
Fingers domain of DNA polymerase lambda/DNA p
— OG7
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000711100 ⚠
Glutathione S-transferase, N-terminal domain/
— OG7
LAMA_000187400 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000587200 ⚠
Leucine Rich repeat/Leucine Rich Repeat, puta
— OG7
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000507400 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000063500 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000324100
Aldehyde dehydrogenase family, putative
— Both
LAMA_000799000 ⚠
Cys/Met metabolism PLP-dependent enzyme/DegT/
— Both
LAMA_000236100
Bacterial NAD-glutamate dehydrogenase/Glutama
— Both
LAMA_000434700
AhpC/TSA family/Redoxin/C-terminal domain of
— Both
LAMA_000437900
Vacuolar (H+)-ATPase G subunit, putative
— Both
LAMA_000214400 ⚠
Cys/Met metabolism PLP-dependent enzyme, puta
— Both
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— Both
LAMA_000590200
WD domain, G-beta repeat/Anaphase-promoting c
— Both
LAMA_000503100
Glycine cleavage system P-protein, putative
— Both
LAMA_000756700
Aldose 1-epimerase, putative
— Both
LAMA_000149700 ⚠
Glutathione S-transferase, N-terminal domain/
— Both
LAMA_000538200
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— Both
LAMA_000288700 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000211300 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000423100
tRNA-methyltransferase O, putative
— Both
LAMA_000595500
hypothetical protein, conserved
— Both
LAMA_000688100
Glucosamine-6-phosphate isomerases/6-phosphog
— Both
LAMA_000656200
hypothetical protein, conserved
— Both
LAMA_000353700
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.