LAMA_000747000

Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1/OB-fold nucleic acid binding domain/tRNA synthetases class II (D, K and N), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_103052 OG7: OG7_0002299 315 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 315 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000186300 ⚠
tRNA synthetases class I (C) catalytic domain
— +2 more Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— +1 more Both
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000781200 ⚠
TGS domain/Threonyl and Alanyl tRNA synthetas
— Both
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— +1 more Both
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— +1 more Both
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— +1 more Both
LAMA_000285400 ⚠
Aminoacyl-tRNA editing domain/tRNA synthetase
— +1 more Both
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— Both
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— Both
LAMA_000591800 ⚠
hypothetical protein, conserved
— Both
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000270000 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000202000 ⚠
N2,N2-dimethylguanosine tRNA methyltransferas
— OG7
LAMA_000544700 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000580200 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000667600 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAMA_000154000 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAMA_000270100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000270200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000579000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000592800 ⚠
CS domain containing protein, putative
— OG7
LAMA_000349800 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000589800 ⚠
hypothetical protein
— OG7
LAMA_000357700 ⚠
VHS domain containing protein, putative
— OG7
LAMA_000500300 ⚠
PCI domain containing protein, putative
— OG7
LAMA_000412200 ⚠
Dehydrogenase E1 component, putative
— OG7
LAMA_000785300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000395100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000760000 ⚠
ATP synthase alpha/beta family, beta-barrel d
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— OG7
LAMA_000317300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000600500 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000542900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.