LAMA_000362600

tRNA synthetases class I (I, L, M and V)/Anticodon-binding domain of tRNA, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100811 OG7: OG7_0003029 189 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 189 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— Both
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— +1 more Both
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— +1 more Both
LAMA_000203600
tRNA synthetases class I (I, L, M and V)/tRNA
— Both
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— +1 more Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— Both
LAMA_000633600 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000487100 ⚠
hypothetical protein, conserved
— Both
LAMA_000193200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000700000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000739200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000471700 ⚠
SET domain containing protein, putative
— OG7
LAMA_000444800 ⚠
SET domain containing protein, putative
— OG7
LAMA_000530200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000676000 ⚠
Importin repeat, putative
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000186600
Pyridoxal-dependent decarboxylase, pyridoxal
— Both
LAMA_000482300
Translation initiation factor SUI1, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000593200 ⚠
GrpE, putative
— Both
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAMA_000268400
Mak10 subunit, NatC N(alpha)-terminal acetylt
— Both
LAMA_000812000
SET domain containing protein, putative
— Both
LAMA_000393700
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— Both
LAMA_000282000
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000532400 ⚠
Nucleoporin autopeptidase/Nuclear protein 96,
— Both
LAMA_000499400
Translation initiation factor eIF3 subunit, p
— Both
LAMA_000401100
La domain containing protein, putative
— Both
LAMA_000777700
Protein tyrosine kinase/Protein kinase domain
— OG6
LAMA_000781300
Tetratricopeptide repeat, putative
— Both
LAMA_000771800
hypothetical protein, conserved
— Both
LAMA_000291700
CrtC N-terminal lipocalin domain/Lipocalin-li
— Both
LAMA_000771500
hypothetical protein, conserved
— Both
LAMA_000479800 ⚠
Metallo-beta-lactamase superfamily domain/Cle
— Both
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— Both
LAMA_000578700 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000771900
hypothetical protein, conserved
— Both
LAMA_000458300 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000502500
hypothetical protein, conserved
— Both
LAMA_000016200
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— Both
LAMA_000388900
PRP38 family, putative
— Both
LAMA_000776200
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.