LAMA_000812000

SET domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_108008 OG7: OG7_0013020 182 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 182 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000559100 ⚠
RNB domain containing protein, putative
— +1 more Both
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— Both
LAMA_000487100 ⚠
hypothetical protein, conserved
— Both
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000495300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000328500 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000103100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000715300
Histone-binding protein RBBP4 or subunit C of
— Both
LAMA_000488800
hypothetical protein, conserved
— Both
LAMA_000334500 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG6
LAMA_000244600 ⚠
Met-10+ like-protein, putative
— Both
LAMA_000779000 ⚠
DEAD/DEAH box helicase/AAA domain/Helicase co
— OG6
LAMA_000464700 ⚠
Helicase conserved C-terminal domain/Helicase
— OG6
LAMA_000771900
hypothetical protein, conserved
— Both
LAMA_000306300 ⚠
Tetratricopeptide repeat, putative
— OG6
LAMA_000553400 ⚠
Tetratricopeptide repeat/Potential Monad-bind
— OG6
LAMA_000107300
Thioredoxin-like domain/UDP-glucose:Glycoprot
— Both
LAMA_000479800 ⚠
Metallo-beta-lactamase superfamily domain/Cle
— Both
LAMA_000432800
tRNA synthetases class II (A)/Threonyl and Al
— Both
LAMA_000743000
EAP30/Vps36 family, putative
— Both
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000633600 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000549400
Ribonucleotide reductase, small chain, putati
— Both
LAMA_000694600
Gar1/Naf1 RNA binding region containing prote
— Both
LAMA_000070300
hypothetical protein, conserved
— Both
LAMA_000486500
DNL zinc finger containing protein, putative
— Both
LAMA_000291700
CrtC N-terminal lipocalin domain/Lipocalin-li
— Both
LAMA_000362600
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000369100
hypothetical protein, conserved
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000414100
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000384900
hypothetical protein, conserved
— Both
LAMA_000186600
Pyridoxal-dependent decarboxylase, pyridoxal
— Both
LAMA_000107800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000749800 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000181600 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000264200 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000264000 ⚠
Acyl CoA binding protein, putative
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000720700 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000515300 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000811100 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000703300 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.