LAMA_000479800

Metallo-beta-lactamase superfamily domain/Cleavage and polyadenylation factor 2 C-terminal, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_103283 OG7: OG7_0002417 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— Both
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000306900 ⚠
PUB domain containing protein, putative
— Both
LAMA_000404000 ⚠
tRNA synthetases class I (I, L, M and V)/tRNA
— Both
LAMA_000297600 ⚠
ABC transporter, putative
— Both
LAMA_000393700 ⚠
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— Both
LAMA_000282000
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000499400 ⚠
Translation initiation factor eIF3 subunit, p
— Both
LAMA_000532400 ⚠
Nucleoporin autopeptidase/Nuclear protein 96,
— Both
LAMA_000812000 ⚠
SET domain containing protein, putative
— Both
LAMA_000388900 ⚠
PRP38 family, putative
— Both
LAMA_000016200 ⚠
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— Both
LAMA_000435400 ⚠
MobA-like NTP transferase domain/Nucleotidyl
— Both
LAMA_000502500 ⚠
hypothetical protein, conserved
— Both
LAMA_000487100 ⚠
hypothetical protein, conserved
— Both
LAMA_000578700 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— Both
LAMA_000532300 ⚠
hypothetical protein
— Both
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000432800 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— Both
LAMA_000559100 ⚠
RNB domain containing protein, putative
— Both
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— Both
LAMA_000694600 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LAMA_000070300 ⚠
hypothetical protein, conserved
— Both
LAMA_000463100 ⚠
hypothetical protein, conserved
— Both
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000153100 ⚠
ATPase family associated with various cellula
— Both
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000742500 ⚠
N-terminal region of Chorein or VPS13/Vacuola
— OG7
LAMA_000592800 ⚠
CS domain containing protein, putative
— OG7
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000395100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000390000 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAMA_000055100 ⚠
Ankyrin repeat/DHHC palmitoyltransferase, put
— OG7
LAMA_000766400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LAMA_000044900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000793100 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000696200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000055200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000116800 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000043100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000284400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.