LAMA_000435400

MobA-like NTP transferase domain/Nucleotidyl transferase/Bacterial transferase hexapeptide (six repeats), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100460 OG7: OG7_0001668 178 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 178 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000078900
Glutamine synthetase, beta-Grasp domain/Gluta
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000656400
Histone chaperone Rttp106-like, putative
— Both
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— Both
LAMA_000694600
Gar1/Naf1 RNA binding region containing prote
— Both
LAMA_000070300
hypothetical protein, conserved
— Both
LAMA_000520200 ⚠
hypothetical protein, conserved
— Both
LAMA_000168600 ⚠
hypothetical protein, conserved
— Both
LAMA_000362600
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000128200 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000337200
hypothetical protein, conserved
— Both
LAMA_000128600
Metallopeptidase family M24/FACT complex subu
— Both
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— +2 more Both
LAMA_000437200
short chain dehydrogenase/Enoyl-(Acyl carrier
— Both
LAMA_000306900
PUB domain containing protein, putative
— Both
LAMA_000404000
tRNA synthetases class I (I, L, M and V)/tRNA
— Both
LAMA_000393700
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— Both
LAMA_000416700
ATP synthase, putative
— Both
LAMA_000063800
Biotin-requiring enzyme/e3 binding domain/2-o
— Both
LAMA_000136600 ⚠
Helix-hairpin-helix domain/Fingers domain of
— Both
LAMA_000147500
Putative zinc finger in N-recognin (UBR box),
— Both
LAMA_000502500
hypothetical protein, conserved
— Both
LAMA_000578700 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000132900
WD domain, G-beta repeat, putative
— Both
LAMA_000159500
Exonuclease, putative
— Both
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— Both
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000501300
hypothetical protein, conserved
— Both
LAMA_000774200
ATP synthase subunit D, putative
— Both
LAMA_000349600
Leucine Rich repeat, putative
— OG6
LAMA_000591800
hypothetical protein, conserved
— Both
LAMA_000474600
Tubulin folding cofactor D C terminal, putati
— Both
LAMA_000644600
hypothetical protein, conserved
— Both
LAMA_000297600 ⚠
ABC transporter, putative
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000692400 ⚠
Methyltransferase TYW3, putative
— OG7
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000270000 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000284400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000542900
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.