LAMA_000520200

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102412 OG7: OG7_0006233 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000159500 ⚠
Exonuclease, putative
— Both
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— Both
LAMA_000591800 ⚠
hypothetical protein, conserved
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000656400 ⚠
Histone chaperone Rttp106-like, putative
— Both
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— Both
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG7
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000292100 ⚠
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000781200 ⚠
TGS domain/Threonyl and Alanyl tRNA synthetas
— Both
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— Both
LAMA_000747200 ⚠
Uncharacterized conserved protein H4 (DUF2046
— Both
LAMA_000662900 ⚠
PheRS DNA binding domain 1/PheRS DNA binding
— Both
LAMA_000462000 ⚠
SacI homology domain/Protein of unknown funct
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000237000 ⚠
Endonuclease/Exonuclease/phosphatase family/R
— OG7
LAMA_000741600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000158000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000808900 ⚠
SacI homology domain containing protein, puta
— OG7
LAMA_000800400 ⚠
hypothetical protein, conserved
— Both
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000542900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000317300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000437200 ⚠
short chain dehydrogenase/Enoyl-(Acyl carrier
— Both
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— Both
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— +2 more Both
LAMA_000128600 ⚠
Metallopeptidase family M24/FACT complex subu
— Both
LAMA_000186300 ⚠
tRNA synthetases class I (C) catalytic domain
— Both
LAMA_000337200 ⚠
hypothetical protein, conserved
— Both
LAMA_000774200 ⚠
ATP synthase subunit D, putative
— Both
LAMA_000389300 ⚠
hypothetical protein
— OG6
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— Both
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.