LAMA_000158000

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_156829 OG7: OG7_0043625 106 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 106 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000423700
hypothetical protein, conserved
— OG7
LAMA_000349800 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000128600
Metallopeptidase family M24/FACT complex subu
— OG7
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000437200
short chain dehydrogenase/Enoyl-(Acyl carrier
— OG7
LAMA_000785300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000412200
Dehydrogenase E1 component, putative
— OG7
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG7
LAMA_000714300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000416700
ATP synthase, putative
— OG7
LAMA_000063800
Biotin-requiring enzyme/e3 binding domain/2-o
— OG7
LAMA_000125500
STI1 domain containing protein, putative
— OG7
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG7
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG7
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000132900
WD domain, G-beta repeat, putative
— OG7
LAMA_000159500
Exonuclease, putative
— OG7
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG7
LAMA_000411500
V-ATPase subunit H, putative
— OG7
LAMA_000415500 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000220700 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000337300
ATP synthase (E/31 kDa) subunit, putative
— OG7
LAMA_000227200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000147500
Putative zinc finger in N-recognin (UBR box),
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000656400
Histone chaperone Rttp106-like, putative
— OG7
LAMA_000617700
hypothetical protein, conserved
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000636000
SPRY domain containing protein, putative
— OG7
LAMA_000474600
Tubulin folding cofactor D C terminal, putati
— OG7
LAMA_000579400
ATP synthase alpha/beta family, beta-barrel d
— OG7
LAMA_000435400
MobA-like NTP transferase domain/Nucleotidyl
— OG7
LAMA_000168600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000520200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000285400
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000360600
Splicing factor 1 helix-hairpin domain/KH dom
— OG7
LAMA_000016200
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— OG7
LAMA_000031500
Aspartyl protease/gag-polyprotein putative as
— OG7
LAMA_000448200
Domain of unknown function (DUF1899)/Type of
— OG7
LAMA_000583300
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000285900
hypothetical protein, conserved
— OG7
LAMA_000760000
ATP synthase alpha/beta family, beta-barrel d
— OG7
LAMA_000542900
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.