LAMA_000285400

Aminoacyl-tRNA editing domain/tRNA synthetase class II core domain (G, H, P, S and T)/Anticodon binding domain/Prolyl-tRNA synthetase, C-terminal, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100749 OG7: OG7_0002333 182 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 182 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000278400
hypothetical protein, conserved
— Both
LAMA_000186300
tRNA synthetases class I (C) catalytic domain
— +2 more Both
LAMA_000423700
hypothetical protein, conserved
— Both
LAMA_000474600
Tubulin folding cofactor D C terminal, putati
— +2 more Both
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— +1 more Both
LAMA_000285900
hypothetical protein, conserved
— Both
LAMA_000715300
Histone-binding protein RBBP4 or subunit C of
— Both
LAMA_000719300
PPPDE putative peptidase domain/PUB domain/Gl
— Both
LAMA_000636000
SPRY domain containing protein, putative
— OG7
LAMA_000643700
hypothetical protein, conserved
— Both
LAMA_000437700
hypothetical protein, conserved
— Both
LAMA_000513400
hypothetical protein, conserved
— Both
LAMA_000266300 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— OG6
LAMA_000104800
Aminopeptidase I zinc metalloprotease (M18)/M
— Both
LAMA_000304500 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— Both
LAMA_000602700
CLASP N terminal, putative
— Both
LAMA_000299500
hypothetical protein, conserved
— Both
LAMA_000405800
Domain of unknown function (DUF4042), putativ
— Both
LAMA_000423100
tRNA-methyltransferase O, putative
— Both
LAMA_000179200
PUB domain containing protein, putative
— Both
LAMA_000097900
Domain of unknown function (DUF3437), putativ
— Both
LAMA_000189000 ⚠
WW domain containing protein, putative
— Both
LAMA_000132900
WD domain, G-beta repeat, putative
— Both
LAMA_000031500
Aspartyl protease/gag-polyprotein putative as
— Both
LAMA_000598500
Zinc finger, C3HC4 type (RING finger) contain
— Both
LAMA_000178900
Leucine Rich repeat, putative
— Both
LAMA_000012800
Soluble NSF attachment protein, SNAP, putativ
— Both
LAMA_000283700
Hydantoinase/oxoprolinase N-terminal region/H
— Both
LAMA_000349600
Leucine Rich repeat, putative
— OG6
LAMA_000202000
N2,N2-dimethylguanosine tRNA methyltransferas
— Both
LAMA_000274400 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
LAMA_000070600 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000310700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000125800 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000811100 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000661500 ⚠
Leucine rich repeat, putative
— OG7
LAMA_000626200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000544700 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000495300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.