LAMA_000097900

Domain of unknown function (DUF3437), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_199775 OG7: OG7_0052363 103 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 103 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000132900
WD domain, G-beta repeat, putative
— Both
LAMA_000198700
hypothetical protein, conserved
— Both
LAMA_000179600
hypothetical protein, conserved
— Both
LAMA_000104800
Aminopeptidase I zinc metalloprotease (M18)/M
— Both
LAMA_000460200 ⚠
PPPDE putative peptidase domain containing pr
— Both
LAMA_000253200
hypothetical protein, conserved
— Both
LAMA_000400200
Vacuolar protein sorting-associated protein 3
— Both
LAMA_000230700 ⚠
Ecotin, putative
— Both
LAMA_000397100
CHAT domain containing protein, putative
— Both
LAMA_000388500
hypothetical protein, conserved
— Both
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000661500 ⚠
Leucine rich repeat, putative
— OG7
LAMA_000371900
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000221400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000544700 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000270100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000270200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000388300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000083500 ⚠
TLD, putative
— OG7
LAMA_000326300 ⚠
TLD, putative
— OG7
LAMA_000336300 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000127800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000154000 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000456400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000228800 ⚠
Ecotin, putative
— OG7
LAMA_000579000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000667600 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAMA_000580200 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000356200 ⚠
Leucine rich repeat/Leucine-rich repeat, puta
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000534400 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000214400 ⚠
Cys/Met metabolism PLP-dependent enzyme, puta
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.