LAMA_000544700

Eukaryotic initiation factor 4E, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100627 OG7: OG7_0002303 204 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 204 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000714900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— OG7
LAMA_000566900 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000579000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000270200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000270100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000189000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000035500 ⚠
Vps51/Vps67, putative
— OG7
LAMA_000420600 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000304300 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000524500 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000087800 ⚠
Adaptin N terminal region containing protein,
— OG7
LAMA_000023400 ⚠
Vps23 core domain containing protein, putativ
— OG7
LAMA_000435500 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000453900 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000814500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000724100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAMA_000671800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000743400 ⚠
Protein of unknown function (DUF3808), putati
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000323800 ⚠
Sec34-like family, putative
— OG7
LAMA_000763300 ⚠
Adaptin N terminal region/Adaptin C-terminal
— OG7
LAMA_000359300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000721300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000534400 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000196200 ⚠
Alba, putative
— OG7
LAMA_000454200 ⚠
ANTH domain containing protein, putative
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG7
LAMA_000463700 ⚠
Rad17 P-loop domain/ATPase family associated
— OG7
LAMA_000136400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000285400 ⚠
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000612400 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000799300 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000733000 ⚠
Conserved oligomeric complex COG6, putative
— OG7
LAMA_000723700 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
LAMA_000313500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000553600 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000388300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000270300 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000651000 ⚠
Aldo/keto reductase family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.