LAMA_000307100

Histidine phosphatase superfamily (branch 1), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_129420 OG7: OG7_0002306 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000796000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
LAMA_000700500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000435400 ⚠
MobA-like NTP transferase domain/Nucleotidyl
— OG7
LAMA_000501300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000800400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000662900 ⚠
PheRS DNA binding domain 1/PheRS DNA binding
— OG7
LAMA_000747200 ⚠
Uncharacterized conserved protein H4 (DUF2046
— OG7
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG7
LAMA_000781200 ⚠
TGS domain/Threonyl and Alanyl tRNA synthetas
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000159500 ⚠
Exonuclease, putative
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG7
LAMA_000158000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000411500 ⚠
V-ATPase subunit H, putative
— OG7
LAMA_000415500 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000337300 ⚠
ATP synthase (E/31 kDa) subunit, putative
— OG7
LAMA_000220700 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000741600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000656400 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LAMA_000237000 ⚠
Endonuclease/Exonuclease/phosphatase family/R
— OG7
LAMA_000227200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000405800 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
LAMA_000125800 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000171400 ⚠
Seryl-tRNA synthetase N-terminal domain/tRNA
— OG7
LAMA_000054500 ⚠
Lyase/Adenylosuccinate lyase C-terminal, puta
— OG7
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000507400 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000053500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000656200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000306900 ⚠
PUB domain containing protein, putative
— OG7
LAMA_000076700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000682400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000610600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000023000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000760000 ⚠
ATP synthase alpha/beta family, beta-barrel d
— OG7
LAMA_000636000 ⚠
SPRY domain containing protein, putative
— OG7
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— OG7
LAMA_000617700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000197000 ⚠
Lipase (class 3), putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.