LAMA_000656200

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147241 OG7: OG7_0052322 27 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 27 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000207500
hypothetical protein, conserved
— Both
LAMA_000063500 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000507400 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000587200 ⚠
Leucine Rich repeat/Leucine Rich Repeat, puta
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000745800 ⚠
Endonuclease/Exonuclease/phosphatase family,
— OG7
LAMA_000076700
hypothetical protein, conserved
— Both
LAMA_000053500
hypothetical protein, conserved
— Both
LAMA_000548100
Protein tyrosine kinase/Kinase-like/Protein k
— OG6
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— Both
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— Both
LAMA_000299400
Phe-tRNA synthetase beta subunit B1 domain/B3
— Both
LAMA_000306900
PUB domain containing protein, putative
— Both
LAMA_000078900
Glutamine synthetase, beta-Grasp domain/Gluta
— Both
LAMA_000564700
short chain dehydrogenase/Enoyl-(Acyl carrier
— Both
LAMA_000564400 ⚠
hypothetical protein, conserved
— Both
LAMA_000197000
Lipase (class 3), putative
— Both
LAMA_000610600
hypothetical protein, conserved
— Both
LAMA_000701800
hypothetical protein, conserved
— Both
LAMA_000721800
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000023000
hypothetical protein, conserved
— Both
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— Both
LAMA_000682400
hypothetical protein, conserved
— Both
LAMA_000796000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LAMA_000700500
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.