LAMA_000548100

Protein tyrosine kinase/Kinase-like/Protein kinase domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147591 OG7: OG7_0000396 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000362800
hypothetical protein, conserved
— OG6
LAMA_000563400
'Cold-shock' DNA-binding domain containing pr
— OG6
LAMA_000306900
PUB domain containing protein, putative
— OG6
LAMA_000700500
hypothetical protein, conserved
— OG6
LAMA_000796000
Leucine carboxyl methyltransferase/Cupin-like
— OG6
LAMA_000682400
hypothetical protein, conserved
— OG6
LAMA_000610600
hypothetical protein, conserved
— OG6
LAMA_000364000
Rab3 GTPase-activating protein regulatory sub
— OG6
LAMA_000349600
Leucine Rich repeat, putative
— OG6
LAMA_000656200
hypothetical protein, conserved
— OG6
LAMA_000023000
hypothetical protein, conserved
— OG6
LAMA_000612500
Stabilization of polarity axis, putative
— OG6
LAMA_000800300
Putative death-receptor fusion protein (DUF24
— OG6
LAMA_000248900
Ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LAMA_000451500
Inositol hexakisphosphate, putative
— OG6
LAMA_000082800
hypothetical protein, conserved
— OG6
LAMA_000053500
hypothetical protein, conserved
— OG6
LAMA_000076700
hypothetical protein, conserved
— OG6
LAMA_000207500
hypothetical protein, conserved
— OG6
LAMA_000060400
Transcriptional repressor TCF25, putative
— OG6
LAMA_000045700
hypothetical protein, conserved
— OG6
LAMA_000197000
Lipase (class 3), putative
— OG6
LAMA_000466400
hypothetical protein, conserved
— OG6
LAMA_000456600
hypothetical protein, conserved
— OG6
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— OG6
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— OG6
LAMA_000295800
hypothetical protein, conserved
— OG6
LAMA_000043700
hypothetical protein, conserved
— OG6
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— OG6
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG6
LAMA_000389300 ⚠
hypothetical protein
— OG6
LAMA_000389400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000299500
hypothetical protein, conserved
— OG6
LAMA_000582600
Uncharacterized ACR, COG1678, putative
— OG6
LAMA_000564700
short chain dehydrogenase/Enoyl-(Acyl carrier
— OG6
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.