LAMA_000563400

'Cold-shock' DNA-binding domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100504 OG7: OG7_0002341 38 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 38 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000451500 ⚠
Inositol hexakisphosphate, putative
— Both
LAMA_000612500 ⚠
Stabilization of polarity axis, putative
— Both
LAMA_000800300 ⚠
Putative death-receptor fusion protein (DUF24
— Both
LAMA_000602700 ⚠
CLASP N terminal, putative
— Both
LAMA_000389300 ⚠
hypothetical protein
— OG6
LAMA_000389400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000548100
Protein tyrosine kinase/Kinase-like/Protein k
— OG6
LAMA_000248900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000181500 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000362800 ⚠
hypothetical protein, conserved
— Both
LAMA_000082800 ⚠
hypothetical protein, conserved
— Both
LAMA_000459900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000399200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000598200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000322500 ⚠
Zinc knuckle, putative
— OG7
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— Both
LAMA_000023000 ⚠
hypothetical protein, conserved
— Both
LAMA_000045700 ⚠
hypothetical protein, conserved
— Both
LAMA_000322600 ⚠
Zinc knuckle, putative
— Both
LAMA_000322900 ⚠
Zinc knuckle, putative
— OG6
LAMA_000466400 ⚠
hypothetical protein, conserved
— Both
LAMA_000456600 ⚠
hypothetical protein, conserved
— Both
LAMA_000504800 ⚠
Eukaryotic initiation factor 4E, putative
— Both
LAMA_000434800
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000516900
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000043700 ⚠
hypothetical protein, conserved
— Both
LAMA_000240700 ⚠
hypothetical protein, conserved
— Both
LAMA_000749600 ⚠
Alba, putative
— Both
LAMA_000167100 ⚠
MIF4G domain containing protein, putative
— Both
LAMA_000028800 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000295800 ⚠
hypothetical protein, conserved
— Both
LAMA_000582600 ⚠
Uncharacterized ACR, COG1678, putative
— Both
LAMA_000796000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LAMA_000364000 ⚠
Rab3 GTPase-activating protein regulatory sub
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.