LAMA_000023000

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147185 OG7: OG7_0043783 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000167100
MIF4G domain containing protein, putative
— Both
LAMA_000507400 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000050400
3'5'-cyclic nucleotide phosphodiesterase, put
— Both
LAMA_000406700
Aminoacyl-tRNA editing domain containing prot
— Both
LAMA_000654400
hypothetical protein, conserved
— Both
LAMA_000564700
short chain dehydrogenase/Enoyl-(Acyl carrier
— Both
LAMA_000207500
hypothetical protein, conserved
— Both
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— Both
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— Both
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000548100
Protein tyrosine kinase/Kinase-like/Protein k
— OG6
LAMA_000053500
hypothetical protein, conserved
— Both
LAMA_000076700
hypothetical protein, conserved
— Both
LAMA_000587200 ⚠
Leucine Rich repeat/Leucine Rich Repeat, puta
— OG7
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— Both
LAMA_000063500 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000295600
Core histone H2A/H2B/H3/H4/Histone-like trans
— OG7
LAMA_000322500 ⚠
Zinc knuckle, putative
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000260500 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— OG7
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000635700 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LAMA_000037700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000406800 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— Both
LAMA_000656200
hypothetical protein, conserved
— Both
LAMA_000637300
hypothetical protein, conserved
— Both
LAMA_000262000
hypothetical protein, conserved
— Both
LAMA_000236100
Bacterial NAD-glutamate dehydrogenase/Glutama
— Both
LAMA_000037800 ⚠
hypothetical protein, conserved
— Both
LAMA_000504800
Eukaryotic initiation factor 4E, putative
— Both
LAMA_000434800
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000563400 ⚠
'Cold-shock' DNA-binding domain containing pr
— Both
LAMA_000111100 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— Both
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— Both
LAMA_000240700
hypothetical protein, conserved
— Both
LAMA_000749600
Alba, putative
— Both
LAMA_000725800
hypothetical protein, conserved
— Both
LAMA_000610600
hypothetical protein, conserved
— Both
LAMA_000322600 ⚠
Zinc knuckle, putative
— Both
LAMA_000322900 ⚠
Zinc knuckle, putative
— OG6
LAMA_000197000
Lipase (class 3), putative
— Both
LAMA_000290700
Fibrillarin/tRNA methyltransferase complex GC
— Both
LAMA_000726100
hypothetical protein, conserved
— Both
LAMA_000714900
hypothetical protein, conserved
— Both
LAMA_000306900
PUB domain containing protein, putative
— Both
LAMA_000700500
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.