LAMA_000349600

Leucine Rich repeat, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_110710 OG7: OG7_0002649 122 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 122 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— Both
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— Both
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— Both
LAMA_000796000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— Both
LAMA_000411500
V-ATPase subunit H, putative
— OG6
LAMA_000276300
ATP12 chaperone protein, putative
— OG6
LAMA_000412200
Dehydrogenase E1 component, putative
— OG6
LAMA_000500300
PCI domain containing protein, putative
— OG6
LAMA_000274400
zinc-finger of a C2HC-type/Double zinc ribbon
— OG6
LAMA_000285900
hypothetical protein, conserved
— OG6
LAMA_000684300
Ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG6
LAMA_000389400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000715300
Histone-binding protein RBBP4 or subunit C of
— OG6
LAMA_000416700
ATP synthase, putative
— OG6
LAMA_000278400
hypothetical protein, conserved
— OG6
LAMA_000776200
hypothetical protein, conserved
— OG6
LAMA_000016200
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— OG6
LAMA_000063800
Biotin-requiring enzyme/e3 binding domain/2-o
— OG6
LAMA_000147500
Putative zinc finger in N-recognin (UBR box),
— OG6
LAMA_000125500
STI1 domain containing protein, putative
— OG6
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG6
LAMA_000435400
MobA-like NTP transferase domain/Nucleotidyl
— OG6
LAMA_000501300
hypothetical protein, conserved
— OG6
LAMA_000800400
hypothetical protein, conserved
— OG6
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG6
LAMA_000781200
TGS domain/Threonyl and Alanyl tRNA synthetas
— OG6
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000292100
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG6
LAMA_000132900
WD domain, G-beta repeat, putative
— OG6
LAMA_000159500
Exonuclease, putative
— OG6
LAMA_000131000
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG6
LAMA_000790400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000619900 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000191700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000386600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000332300 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000687100 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000600100 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000609300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000398500 ⚠
Vps51/Vps67/Dor1-like family/Exocyst complex
— OG7
LAMA_000592100 ⚠
Ciliary BBSome complex subunit 2, middle regi
— OG7
LAMA_000654000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000367100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000121400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000666700 ⚠
PTHB1 N-terminus/PTHB1 C-terminus, putative
— OG7
LAMA_000474600
Tubulin folding cofactor D C terminal, putati
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.