LAMA_000292100

Microtubule binding/Kinesin motor domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_104312 OG7: OG7_0000136 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000593700
hypothetical protein, conserved
— OG6
LAMA_000781200
TGS domain/Threonyl and Alanyl tRNA synthetas
— OG6
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000132900
WD domain, G-beta repeat, putative
— OG6
LAMA_000159500
Exonuclease, putative
— OG6
LAMA_000268400
Mak10 subunit, NatC N(alpha)-terminal acetylt
— OG6
LAMA_000131000
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG6
LAMA_000656400
Histone chaperone Rttp106-like, putative
— OG6
LAMA_000747200
Uncharacterized conserved protein H4 (DUF2046
— OG6
LAMA_000589400
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000747000
Glutaminyl-tRNA synthetase, non-specific RNA
— OG6
LAMA_000800400
hypothetical protein, conserved
— OG6
LAMA_000505500
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG6
LAMA_000715300
Histone-binding protein RBBP4 or subunit C of
— OG6
LAMA_000684300
Ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LAMA_000501300
hypothetical protein, conserved
— OG6
LAMA_000670900
hypothetical protein, conserved
— OG6
LAMA_000031500
Aspartyl protease/gag-polyprotein putative as
— OG6
LAMA_000473300
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG6
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG6
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG6
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG6
LAMA_000520200 ⚠
hypothetical protein, conserved
— OG6
LAMA_000168600 ⚠
hypothetical protein, conserved
— OG6
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000774200
ATP synthase subunit D, putative
— OG6
LAMA_000349600
Leucine Rich repeat, putative
— OG6
LAMA_000591800
hypothetical protein, conserved
— OG6
LAMA_000474600
Tubulin folding cofactor D C terminal, putati
— OG6
LAMA_000293900 ⚠
Nucleosome assembly protein (NAP), putative
— OG6
LAMA_000013500
M17 aminopeptidase N-terminal domain 2, putat
— OG6
LAMA_000375400
Adaptin N terminal region/HEAT repeats/non-SM
— OG6
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG6
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG6
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG6
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG6
LAMA_000560300
Modifier of rudimentary (Mod(r)) protein, put
— OG6
LAMA_000454100
Mitochondrial branched-chain alpha-ketoacid d
— OG6
LAMA_000764500
GRIP domain containing protein, putative
— OG6
LAMA_000448200
Domain of unknown function (DUF1899)/Type of
— OG6
LAMA_000299400
Phe-tRNA synthetase beta subunit B1 domain/B3
— OG6
LAMA_000662900
PheRS DNA binding domain 1/PheRS DNA binding
— OG6
LAMA_000389300 ⚠
hypothetical protein
— OG6
LAMA_000337200
hypothetical protein, conserved
— OG6
LAMA_000766500
Gar1/Naf1 RNA binding region containing prote
— OG6
LAMA_000128600
Metallopeptidase family M24/FACT complex subu
— OG6
LAMA_000186300
tRNA synthetases class I (C) catalytic domain
— OG6
LAMA_000120800
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG6
LAMA_000437200
short chain dehydrogenase/Enoyl-(Acyl carrier
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.