LAMA_000764500

GRIP domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147115 OG7: OG7_0043222 229 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 229 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— Both
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— Both
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000267900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000276600 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000684500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000126100 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000462900 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000723300 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000578900 ⚠
MCM OB domain/MCM P-loop domain/Magnesium che
— OG7
LAMA_000142100 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000065200 ⚠
MCM OB domain/MCM P-loop domain/AAA domain (d
— OG7
LAMA_000815500 ⚠
MCM OB domain/MCM P-loop domain/MCM AAA-lid d
— OG7
LAMA_000684700 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000138300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000149100 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— OG7
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG7
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000789100
hypothetical protein, conserved
— Both
LAMA_000509200
hypothetical protein, conserved
— Both
LAMA_000634500
Protein of unknown function (DUF3638)/Protein
— Both
LAMA_000435500 ⚠
Beige/BEACH domain containing protein, putati
— Both
LAMA_000133900 ⚠
N-terminal domain of ribose phosphate pyropho
— Both
LAMA_000599000
hypothetical protein, conserved
— Both
LAMA_000520200 ⚠
hypothetical protein, conserved
— Both
LAMA_000168600 ⚠
hypothetical protein, conserved
— Both
LAMA_000655600
Armadillo/beta-catenin-like repeat, putative
— Both
LAMA_000349300
Anaphase-promoting complex subunit 4 WD40 dom
— Both
LAMA_000334100
hypothetical protein, conserved
— Both
LAMA_000326900
hypothetical protein, conserved
— Both
LAMA_000329200
Gamma tubulin complex component N-terminal, p
— Both
LAMA_000801400
Acyl transferase domain containing protein, p
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000378400 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.