LAMA_000542000

Ubiquitin carboxyl-terminal hydrolase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101021 OG7: OG7_0001214 209 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 209 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000281400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000764500 ⚠
GRIP domain containing protein, putative
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000440400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000429900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000647100 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— OG7
LAMA_000203300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000566900 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000480300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000450700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000410500 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000448200 ⚠
Domain of unknown function (DUF1899)/Type of
— OG7
LAMA_000098000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000031500 ⚠
Aspartyl protease/gag-polyprotein putative as
— OG7
LAMA_000502900 ⚠
Brix domain containing protein, putative
— OG7
LAMA_000174100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000719300 ⚠
PPPDE putative peptidase domain/PUB domain/Gl
— OG7
LAMA_000192900 ⚠
Protein of unknown function (DUF1698)/Methylt
— OG7
LAMA_000286500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000115400 ⚠
Hsp70 protein/Tetratricopeptide repeat, putat
— OG7
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000159500 ⚠
Exonuclease, putative
— OG7
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG7
LAMA_000158000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000741600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000656400 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000237000 ⚠
Endonuclease/Exonuclease/phosphatase family/R
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000417400 ⚠
Histone deacetylase domain containing protein
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000662900 ⚠
PheRS DNA binding domain 1/PheRS DNA binding
— OG7
LAMA_000008900 ⚠
DNA polymerase family A, putative
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000157700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000670900 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.