LAMA_000042000

ABC transporter, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100624 OG7: OG7_0001747 231 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 231 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000281400 ⚠
hypothetical protein, conserved
— +2 more Both
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000440400 ⚠
hypothetical protein, conserved
— Both
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000367500 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000611000 ⚠
Formate--tetrahydrofolate ligase, putative
— OG7
LAMA_000083600 ⚠
SIS domain containing protein, putative
— OG7
LAMA_000070300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000771500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000219000 ⚠
Eukaryotic glutathione synthase, ATP binding
— OG7
LAMA_000014200 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000488100 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000107300 ⚠
Thioredoxin-like domain/UDP-glucose:Glycoprot
— OG7
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000407400 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000357300 ⚠
Tubulin/FtsZ family, GTPase domain containing
— OG7
LAMA_000812000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000465900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000097100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000587400 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000201400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000652100 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000420500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000592400 ⚠
Histidyl-tRNA synthetase/Anticodon binding do
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000620000 ⚠
DNA ligase N terminus/ATP dependent DNA ligas
— OG7
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— OG7
LAMA_000206000 ⚠
Dpy-30 motif containing protein, putative
— OG7
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000620400 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000061800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000546300 ⚠
Protein tyrosine kinase/Fungal protein kinase
— OG7
LAMA_000493900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000777200 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000179100 ⚠
AAA domain (Cdc48 subfamily)/ATPase family as
— OG7
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— OG7
LAMA_000482300 ⚠
Translation initiation factor SUI1, putative
— OG7
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
LAMA_000310500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.