LAMA_000239500

tRNA synthetases class I (E and Q), catalytic domain/tRNA synthetases class I (E and Q), anti-codon binding domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101072 OG7: OG7_0002336 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000237100 ⚠
DnaJ domain/DnaJ C terminal domain containing
— OG7
LAMA_000362300 ⚠
Adenylate cyclase associated (CAP) N terminal
— OG7
LAMA_000400400 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000578700 ⚠
Serine hydroxymethyltransferase, putative
— OG7
LAMA_000327800 ⚠
DnaJ domain/Domain of unknown function (DUF19
— OG7
LAMA_000418200 ⚠
DnaJ C terminal domain/DnaJ central domain co
— OG7
LAMA_000280600 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000796400 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000688500 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000057700 ⚠
Transmembrane Fragile-X-F protein, putative
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000704300 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000553500 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000489500 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000200700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000122000 ⚠
Radial spokehead-like protein, putative
— OG7
LAMA_000320600 ⚠
EF-1 guanine nucleotide exchange domain conta
— OG7
LAMA_000571200 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000615900 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
LAMA_000338300 ⚠
Adenylate and Guanylate cyclase catalytic dom
— OG7
LAMA_000390600 ⚠
Domain of unknown function (DUF1935), putativ
— OG7
LAMA_000549400 ⚠
Ribonucleotide reductase, small chain, putati
— OG7
LAMA_000738700 ⚠
Myosin head (motor domain), putative
— OG7
LAMA_000797200 ⚠
ThiF family/Ubiquitin-activating enzyme E1 fo
— OG7
LAMA_000442500 ⚠
ThiF family/Ubiquitin-activating enzyme activ
— OG7
LAMA_000321000 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000380400 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000576500 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000737100 ⚠
EF-1 guanine nucleotide exchange domain conta
— OG7
LAMA_000368600 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000475400 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000242200 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000427800 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000458300 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— OG7
LAMA_000503100 ⚠
Glycine cleavage system P-protein, putative
— Both
LAMA_000324100 ⚠
Aldehyde dehydrogenase family, putative
— Both
LAMA_000211300 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000288700 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000538200 ⚠
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— Both
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000149700 ⚠
Glutathione S-transferase, N-terminal domain/
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.