LAMA_000362300

Adenylate cyclase associated (CAP) N terminal/Adenylate cyclase associated (CAP) C terminal, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101374 OG7: OG7_0005390 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000704300 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000327800 ⚠
DnaJ domain/Domain of unknown function (DUF19
— OG7
LAMA_000418200 ⚠
DnaJ C terminal domain/DnaJ central domain co
— OG7
LAMA_000796400 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000688500 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000057700 ⚠
Transmembrane Fragile-X-F protein, putative
— OG7
LAMA_000237100 ⚠
DnaJ domain/DnaJ C terminal domain containing
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000489500 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000186600
Pyridoxal-dependent decarboxylase, pyridoxal
— Both
LAMA_000482300
Translation initiation factor SUI1, putative
— Both
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000578700 ⚠
Serine hydroxymethyltransferase, putative
— Both
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— Both
LAMA_000774700
Proteasome activator pa28 beta subunit, putat
— Both
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000489300
hypothetical protein, conserved
— OG6
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000621500
hypothetical protein, conserved
— Both
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000235700
ThiF family, putative
— Both
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LAMA_000347500
hypothetical protein, conserved
— Both
LAMA_000201400
hypothetical protein, conserved
— Both
LAMA_000115100 ⚠
Clp amino terminal domain, pathogenicity isla
— Both
LAMA_000141900
AAA domain (dynein-related subfamily)/AAA dom
— Both
LAMA_000040200 ⚠
ATPase family associated with various cellula
— Both
LAMA_000789300
Helicase conserved C-terminal domain containi
— OG6
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— +1 more Both
LAMA_000115400 ⚠
Hsp70 protein/Tetratricopeptide repeat, putat
— Both
LAMA_000495000
hypothetical protein, conserved
— Both
LAMA_000010100
FYVE zinc finger containing protein, putative
— Both
LAMA_000180200
Pyruvate phosphate dikinase, PEP/pyruvate bin
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.