LAMA_000621500

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_200263 OG7: OG7_0083588 52 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 52 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000012800
Soluble NSF attachment protein, SNAP, putativ
— Both
LAMA_000549400
Ribonucleotide reductase, small chain, putati
— Both
LAMA_000548400
LSM domain containing protein, putative
— Both
LAMA_000460500 ⚠
Sugar (and other) transporter/Major Facilitat
— Both
LAMA_000489300
hypothetical protein, conserved
— OG6
LAMA_000482300
Translation initiation factor SUI1, putative
— Both
LAMA_000186600
Pyridoxal-dependent decarboxylase, pyridoxal
— Both
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000650300 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000181600 ⚠
Elongation factor Tu GTP binding domain/Elong
— Both
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000697800 ⚠
Sugar (and other) transporter/Major Facilitat
— OG7
LAMA_000010500 ⚠
Sugar (and other) transporter/Major Facilitat
— OG7
LAMA_000454900 ⚠
Calmodulin-binding, putative
— OG7
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000682800
hypothetical protein, conserved
— Both
LAMA_000232500
hypothetical protein, conserved
— Both
LAMA_000601100
hypothetical protein, conserved
— Both
LAMA_000180200
Pyruvate phosphate dikinase, PEP/pyruvate bin
— Both
LAMA_000495000
hypothetical protein, conserved
— Both
LAMA_000115400 ⚠
Hsp70 protein/Tetratricopeptide repeat, putat
— Both
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— +1 more Both
LAMA_000789300
Helicase conserved C-terminal domain containi
— OG6
LAMA_000010100
FYVE zinc finger containing protein, putative
— Both
LAMA_000347500
hypothetical protein, conserved
— Both
LAMA_000743000
EAP30/Vps36 family, putative
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— Both
LAMA_000737200
hypothetical protein, conserved
— Both
LAMA_000106300
Leucine-rich repeat/Leucine rich repeat, puta
— Both
LAMA_000362300
Adenylate cyclase associated (CAP) N terminal
— Both
LAMA_000381100 ⚠
Calmodulin-binding, putative
— Both
LAMA_000511600
hypothetical protein, conserved
— Both
LAMA_000141900
AAA domain (dynein-related subfamily)/AAA dom
— Both
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LAMA_000235700
ThiF family, putative
— Both
LAMA_000027900 ⚠
CUE domain/Domain of unknown function (DUF177
— Both
LAMA_000014300 ⚠
hypothetical protein, conserved
— OG6
LAMA_000128200 ⚠
tRNA synthetases class I (W and Y), putative
— Both
LAMA_000042100
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.