LAMA_000511600

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147158 OG7: OG7_0042643 52 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 52 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000006600 ⚠
Phosphatidylinositol-4-phosphate 5-Kinase, pu
— OG7
LAMA_000203700
hypothetical protein, conserved
— Both
LAMA_000011400 ⚠
Major Facilitator Superfamily, putative
— Both
LAMA_000460500 ⚠
Sugar (and other) transporter/Major Facilitat
— Both
LAMA_000222400
hypothetical protein, conserved
— Both
LAMA_000014400 ⚠
hypothetical protein
— OG7
LAMA_000650300 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LAMA_000697800 ⚠
Sugar (and other) transporter/Major Facilitat
— OG7
LAMA_000010500 ⚠
Sugar (and other) transporter/Major Facilitat
— OG7
LAMA_000777200 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000493900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000546300 ⚠
Protein tyrosine kinase/Fungal protein kinase
— OG7
LAMA_000589800 ⚠
hypothetical protein
— OG7
LAMA_000503900
Phosphoribosyl transferase domain containing
— Both
LAMA_000061800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000367600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000620400 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000753600 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000309400 ⚠
Phosphatidylinositol-4-phosphate 5-Kinase, pu
— OG7
LAMA_000454900 ⚠
Calmodulin-binding, putative
— OG7
LAMA_000044400 ⚠
Major Facilitator Superfamily/Organic Anion T
— OG7
LAMA_000273200 ⚠
Major Facilitator Superfamily, putative
— OG7
LAMA_000395600 ⚠
Major Facilitator Superfamily, putative
— OG7
LAMA_000752000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000694500 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000737200
hypothetical protein, conserved
— Both
LAMA_000236800 ⚠
Cyclic nucleotide-binding domain/PAS fold/Pro
— Both
LAMA_000454000
Nucleoside 2-deoxyribosyltransferase, putativ
— Both
LAMA_000381100 ⚠
Calmodulin-binding, putative
— Both
LAMA_000514600
hypothetical protein, conserved
— Both
LAMA_000184700
hypothetical protein, conserved
— Both
LAMA_000726100
hypothetical protein, conserved
— Both
LAMA_000772900 ⚠
Phosphatidylinositol-4-phosphate 5-Kinase, pu
— Both
LAMA_000611100
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000601100
hypothetical protein, conserved
— Both
LAMA_000621500
hypothetical protein, conserved
— Both
LAMA_000813700
Glycine cleavage H-protein/Biotin-requiring e
— Both
LAMA_000777300 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000292500 ⚠
hypothetical protein, conserved
— Both
LAMA_000368500
hypothetical protein, conserved
— Both
LAMA_000023600
LYAR-type C2HC zinc finger containing protein
— Both
LAMA_000682800
hypothetical protein, conserved
— Both
LAMA_000367500 ⚠
Rab-GTPase-TBC domain containing protein, put
— Both
LAMA_000104100
hypothetical protein, conserved
— Both
LAMA_000328200
hypothetical protein, conserved
— Both
LAMA_000767800 ⚠
ARD/ARD' family, putative
— Both
LAMA_000387000 ⚠
ARD/ARD' family/AraC-like ligand binding doma
— Both
LAMA_000058600
hypothetical protein, conserved
— Both
LAMA_000027900 ⚠
CUE domain/Domain of unknown function (DUF177
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.