LAMA_000752000

Cyclic nucleotide-binding domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_119433 OG7: OG7_0001574 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000395600 ⚠
Major Facilitator Superfamily, putative
— OG7
LAMA_000514600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000044400 ⚠
Major Facilitator Superfamily/Organic Anion T
— OG7
LAMA_000011400 ⚠
Major Facilitator Superfamily, putative
— OG7
LAMA_000772900 ⚠
Phosphatidylinositol-4-phosphate 5-Kinase, pu
— OG7
LAMA_000618200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat/Ank
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000006600 ⚠
Phosphatidylinositol-4-phosphate 5-Kinase, pu
— OG7
LAMA_000710500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000707400 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000380900 ⚠
AAA domain (dynein-related subfamily)/Midasin
— OG7
LAMA_000298300 ⚠
CAP-Gly domain containing protein, putative
— OG7
LAMA_000105900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000298400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000511600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000743500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000390000 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAMA_000055100 ⚠
Ankyrin repeat/DHHC palmitoyltransferase, put
— OG7
LAMA_000014300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000273200 ⚠
Major Facilitator Superfamily, putative
— OG7
LAMA_000766400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LAMA_000496800 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG7
LAMA_000697700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000591000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000668900 ⚠
Microtubule-binding protein MIP-T3 CH-like do
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000742500 ⚠
N-terminal region of Chorein or VPS13/Vacuola
— OG7
LAMA_000653500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000813700 ⚠
Glycine cleavage H-protein/Biotin-requiring e
— OG7
LAMA_000586100 ⚠
MATH domain containing protein, putative
— OG7
LAMA_000667900 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
LAMA_000520700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000657400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000605100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000463100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000401000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000309400 ⚠
Phosphatidylinositol-4-phosphate 5-Kinase, pu
— OG7
LAMA_000382800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000277500 ⚠
Ubiquitin-like domain/CAP-Gly domain containi
— OG7
LAMA_000116800 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000332300 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000484500 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAMA_000217900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000249400 ⚠
N-terminal region of Chorein or VPS13/Vacuola
— OG7
LAMA_000072200 ⚠
Rhodanese-like domain/Domain of unknown funct
— OG7
LAMA_000290700 ⚠
Fibrillarin/tRNA methyltransferase complex GC
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.