LAMA_000463100

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_158151 OG7: OG7_0052371 72 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 72 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000605100
hypothetical protein, conserved
— Both
LAMA_000065900 ⚠
Tetratricopeptide repeat, putative
— +2 more Both
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— +2 more Both
LAMA_000247800 ⚠
Ring finger domain/RING-H2 zinc finger domain
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000742500 ⚠
N-terminal region of Chorein or VPS13/Vacuola
— OG7
LAMA_000247700 ⚠
RING-H2 zinc finger domain/Anaphase-promoting
— OG7
LAMA_000394800 ⚠
Anaphase-promoting complex subunit 11 RING-H2
— OG7
LAMA_000469800 ⚠
Anaphase-promoting complex subunit 11 RING-H2
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000153100
ATPase family associated with various cellula
— Both
LAMA_000484500 ⚠
Raptor N-terminal CASPase like domain contain
— Both
LAMA_000332300
Protein tyrosine kinase/Protein kinase domain
— Both
LAMA_000474000
hypothetical protein, conserved
— Both
LAMA_000117800
Kinesin motor domain/Microtubule binding, put
— OG6
LAMA_000479800 ⚠
Metallo-beta-lactamase superfamily domain/Cle
— Both
LAMA_000572300
Protein kinase domain containing protein, put
— Both
LAMA_000694100
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LAMA_000055200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000257100
WD domain, G-beta repeat, putative
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000390000 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000694500 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000752000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000043100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000116800 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000586100
MATH domain containing protein, putative
— Both
LAMA_000696200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000793100 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000044900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000766400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LAMA_000055100 ⚠
Ankyrin repeat/DHHC palmitoyltransferase, put
— OG7
LAMA_000618200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat/Ank
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000031400 ⚠
hypothetical protein
— Both
LAMA_000063900
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LAMA_000148100
Microtubule-binding stalk of dynein motor, pu
— OG6
LAMA_000053900
Anaphase-promoting complex, subunit 10 (APC10
— Both
LAMA_000055500
Tetratricopeptide repeat, putative
— Both
LAMA_000218100
Kinesin motor domain/Microtubule binding, put
— OG6
LAMA_000179800
hypothetical protein, conserved
— Both
LAMA_000031300 ⚠
Rab-GTPase-TBC domain containing protein, put
— Both
LAMA_000031200 ⚠
hypothetical protein, conserved
— Both
LAMA_000593000
Tetratricopeptide repeat, putative
— Both
LAMA_000079300
ATP-NAD kinase, putative
— Both
LAMA_000249400 ⚠
N-terminal region of Chorein or VPS13/Vacuola
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.