LAMA_000618200

Ankyrin repeats (3 copies)/Ankyrin repeat/Ankyrin repeats (many copies), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100012 OG7: OG7_0000441 143 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 143 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000065100 ⚠
Glutaredoxin, putative
— OG7
LAMA_000607500 ⚠
GYF domain 2/DnaJ domain containing protein,
— OG7
LAMA_000474100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000114300 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000779600 ⚠
Thioredoxin/Glutaredoxin, putative
— OG7
LAMA_000114200 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000740700 ⚠
Uncharacterised ACR, YggU family COG1872, put
— OG7
LAMA_000318000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000522400 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000380900 ⚠
AAA domain (dynein-related subfamily)/Midasin
— OG7
LAMA_000023700 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000105900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000007000 ⚠
hypothetical protein
— OG7
LAMA_000390000 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAMA_000591000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000653500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000586100 ⚠
MATH domain containing protein, putative
— OG7
LAMA_000667900 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
LAMA_000647400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000657400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000605100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000694100 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000572300 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000483500 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000430400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000479800 ⚠
Metallo-beta-lactamase superfamily domain/Cle
— OG7
LAMA_000690600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000026900 ⚠
Glutaredoxin, putative
— OG7
LAMA_000261300 ⚠
Cytidine and deoxycytidylate deaminase zinc-b
— OG7
LAMA_000257100 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000275500 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000474000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000332300 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000484500 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAMA_000463100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000672000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000283700 ⚠
Hydantoinase/oxoprolinase N-terminal region/H
— OG7
LAMA_000088300 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— OG7
LAMA_000013900 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LAMA_000320300 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LAMA_000061600 ⚠
Poly A polymerase head domain/Probable RNA an
— OG7
LAMA_000043100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000184900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000507900 ⚠
ApaG domain containing protein, putative
— OG7
LAMA_000055500 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000012100 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000198000 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000036900 ⚠
Ubiquitin-conjugating enzyme, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.