LAMA_000283700

Hydantoinase/oxoprolinase N-terminal region/Hydantoinase/oxoprolinase/Hydantoinase B/oxoprolinase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100892 OG7: OG7_0005437 120 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 120 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000819600 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000777800
hypothetical protein, conserved
— Both
LAMA_000299400
Phe-tRNA synthetase beta subunit B1 domain/B3
— Both
LAMA_000543000
hypothetical protein, conserved
— Both
LAMA_000415700
hypothetical protein, conserved
— Both
LAMA_000439600
Glycogen recognition site of AMP-activated pr
— Both
LAMA_000153900 ⚠
PPPDE putative peptidase domain containing pr
— Both
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— Both
LAMA_000798700
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LAMA_000643700
hypothetical protein, conserved
— Both
LAMA_000266300 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— OG6
LAMA_000104800
Aminopeptidase I zinc metalloprotease (M18)/M
— Both
LAMA_000304500 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— Both
LAMA_000460200 ⚠
PPPDE putative peptidase domain containing pr
— Both
LAMA_000400200
Vacuolar protein sorting-associated protein 3
— Both
LAMA_000602700
CLASP N terminal, putative
— Both
LAMA_000405800
Domain of unknown function (DUF4042), putativ
— Both
LAMA_000397100
CHAT domain containing protein, putative
— Both
LAMA_000116800 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— Both
LAMA_000797300
Lipocalin-like domain containing protein, put
— Both
LAMA_000559100 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000286000 ⚠
CDP-alcohol phosphatidyltransferase/Cytidylyl
— OG7
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000626300 ⚠
hypothetical protein
— OG7
LAMA_000758900 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LAMA_000336300 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000055200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000284300 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LAMA_000696200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000793100 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000044900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000766400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LAMA_000055100 ⚠
Ankyrin repeat/DHHC palmitoyltransferase, put
— OG7
LAMA_000618200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat/Ank
— OG7
LAMA_000154000 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000626200 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.