LAMA_000104800

Aminopeptidase I zinc metalloprotease (M18)/M42 glutamyl aminopeptidase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102047 OG7: OG7_0006128 201 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 201 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— Both
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000547200 ⚠
Paraflagellar rod protein/Variant SH3 domain/
— OG7
LAMA_000579000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000270200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000270100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000154000 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAMA_000667600 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAMA_000206000 ⚠
Dpy-30 motif containing protein, putative
— OG7
LAMA_000194400 ⚠
Exonuclease/DNA polymerase family A, putative
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000388300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000534400 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000799300 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000612400 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000012800
Soluble NSF attachment protein, SNAP, putativ
— Both
LAMA_000097900
Domain of unknown function (DUF3437), putativ
— Both
LAMA_000179200
PUB domain containing protein, putative
— Both
LAMA_000548200 ⚠
Dpy-30 motif containing protein, putative
— Both
LAMA_000189000 ⚠
WW domain containing protein, putative
— Both
LAMA_000132900
WD domain, G-beta repeat, putative
— Both
LAMA_000023900
lipin, N-terminal conserved region/LNS2 (Lipi
— Both
LAMA_000111300 ⚠
MORN repeat, putative
— Both
LAMA_000418000 ⚠
NF-X1 type zinc finger/R3H domain containing
— Both
LAMA_000178900
Leucine Rich repeat, putative
— Both
LAMA_000209200 ⚠
DNA polymerase family A, putative
— Both
LAMA_000564700
short chain dehydrogenase/Enoyl-(Acyl carrier
— Both
LAMA_000573800
p21-C-terminal region-binding protein, putati
— Both
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000544700 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000763900 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000050100 ⚠
MORN repeat, putative
— OG7
LAMA_000524500
WD domain, G-beta repeat, putative
— Both
LAMA_000312200
Mitochondrial ATP synthase epsilon chain, put
— Both
LAMA_000283700
Hydantoinase/oxoprolinase N-terminal region/H
— Both
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000458400
Leucine-rich repeat/Leucine Rich repeats (2 c
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.